DBCO-PEG3400-NHS
DBCO-PEG3400-NHS is a dibenzocyclooctyne-conjugated polyethylene glycol derivative bearing an NHS group. DBCO-PEG-NHS forms a stable covalent linkage with the amino group of target molecules via the NHS ester at one end, while introducing a DBCO group at the other end, thus preparing for subsequent click chemical conjugation with any azide-bearing molecule or material.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- 분자량:3400 (Average)
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
DBCO-PEG-NHS is used to synthesize targeting antibodies for constructing a pretargeted and bioorthogonal capture system for cardiac repair[1].
DBCO-PEG-NHS is used to functionalize antibodies and liposomes for constructing radioimmunoliposomes targeting vascular endothelial cells[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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분자량 3400 (Average)
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SMILES
O=C(CCC(NCCOCC(ON1C(CCC1=O)=O)=O)=O)N2C3=CC=CC=C3C#CC4=CC=CC=C4C2.[n]
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Li Z, et al. Pretargeting and Bioorthogonal Click Chemistry-Mediated Endogenous Stem Cell Homing for Heart Repair. ACS Nano. 2018;12(12):12193-12200. [Content Brief]
[2]. Hood ED, et al. Vascular Targeting of Radiolabeled Liposomes with Bio-Orthogonally Conjugated Ligands: Single Chain Fragments Provide Higher Specificity than Antibodies. Bioconjug Chem. 2018;29(11):3626-3637. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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