Mrap2 - melanocortin 2 receptor accessory protein 2 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 244958

Summary

Enables signaling receptor regulator activity and type 4 Melanocortin Receptor binding activity. Involved in energy homeostasis; energy reserve metabolic process; and feeding behavior. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum and plasma membrane. Human ortholog(s) of this gene implicated in obesity. Orthologous to human MRAP2 (melanocortin 2 receptor accessory protein 2). [provided by Alliance of Genome Resources, Apr 2022]

Mrap2 Products (3)

mRNA Protein Name
NM_001101482.2 NP_001094952.2 melanocortin-2 receptor accessory protein 2
NM_001177731.1 NP_001171202.1 melanocortin-2 receptor accessory protein 2
NM_001359955.1 NP_001346884.1 melanocortin-2 receptor accessory protein 2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
35311242 MGI
enables signaling receptor regulator activity IMP
IMP: Inferred from mutant phenotype
23869016 MGI
enables type 4 melanocortin receptor binding IDA
IDA: Inferred from direct assay
23869016 MGI
Biological Process GO Annotation Evidence References Source
involved in energy homeostasis IMP
IMP: Inferred from mutant phenotype
23869016 MGI
involved in energy reserve metabolic process IMP
IMP: Inferred from mutant phenotype
23869016 MGI
involved in feeding behavior IMP
IMP: Inferred from mutant phenotype
23869016 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

melanocortin-2 receptor accessory protein 2

Mrap2 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Mrap2 D3Z1Q2 Mchr1 Mus musculus Q8JZL2
BiFC
35311242
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. 상품명
효과
Purity
Rare Diseases
HY-RS08639 MRAP2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22649 Mrap2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29163 Mrap2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Mrap2 NCBI NCBI:112609