Vsig4 - V-set and immunoglobulin domain containing 4 Gene

Also Known as CRIg; Z39IG; A530061A11

Species: Mus musculus

Gene Type: protein coding
Gene ID: 278180

Summary

Predicted to enable complement component C3b binding activity. Acts upstream of or within negative regulation of T cell proliferation and negative regulation of interleukin-2 production. Predicted to be part of protein-containing complex. Is expressed in bone marrow; oviduct; and thyroid gland. Orthologous to human VSIG4 (V-set and immunoglobulin domain containing 4). [provided by Alliance of Genome Resources, Apr 2022]

Vsig4 Products (1)

mRNA Protein Name
NM_177789.5 NP_808457.1 V-set and immunoglobulin domain-containing protein 4 precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence References Source
acts upstream of or within negative regulation of T cell proliferation IDA
IDA: Inferred from direct assay
17016562 MGI
acts upstream of or within negative regulation of interleukin-2 production IDA
IDA: Inferred from direct assay
17016562 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

V-set and immunoglobulin domain-containing protein 4

  • complement receptor of the immunoglobulin superfamily

Recombinant Vsig4 Proteins

Cat. No. Product Name Accession Purity
HY-P71006 VSIG4 Protein, Mouse (HEK293, His) F6TUL9 (H20-P187) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P76699 VSIG4 Protein, Mouse (HEK293, His-Fc) F6TUL9 (H20-P187) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name Effect
Purity Phase
HY-P991217 EU-103 Inhibitor 99.0% Phase 1

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS15709 VSIG4 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17561 Vsig4 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24019 Vsig4 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-P991181 VTX-1218 Inhibitor 99.9% Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Vsig4 NCBI NCBI:11326
Macaca fascicularis Vsig4 NCBI NCBI:102144784