GPR139 agonist-2
Based on 1 Customer Validation
GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research.
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- Purity: 99.85%
- CAS No.: 2983118-29-0
- 화학식: C17H15F3N4O3
- 분자량:380.32
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 2983118-29-0
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Appearance Solid
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분자량 380.32
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화학식 C17H15F3N4O3
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Color White to off-white
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SMILES
O=C1N(CC(N[C@@H](C)C2=CC=C(OC(F)(F)F)C=C2)=O)N=CC3=CC=CN31
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
DMSO : 25 mg/mL (65.73 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6294 mL | 13.1468 mL | 26.2936 mL | 65.7341 mL |
| 5 mM | 0.5259 mL | 2.6294 mL | 5.2587 mL | 13.1468 mL | |
| 10 mM | 0.2629 mL | 1.3147 mL | 2.6294 mL | 6.5734 mL | |
| 15 mM | 0.1753 mL | 0.8765 mL | 1.7529 mL | 4.3823 mL | |
| 20 mM | 0.1315 mL | 0.6573 mL | 1.3147 mL | 3.2867 mL | |
| 25 mM | 0.1052 mL | 0.5259 mL | 1.0517 mL | 2.6294 mL | |
| 30 mM | 0.0876 mL | 0.4382 mL | 0.8765 mL | 2.1911 mL | |
| 40 mM | 0.0657 mL | 0.3287 mL | 0.6573 mL | 1.6434 mL | |
| 50 mM | 0.0526 mL | 0.2629 mL | 0.5259 mL | 1.3147 mL | |
| 60 mM | 0.0438 mL | 0.2191 mL | 0.4382 mL | 1.0956 mL |
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