BF-168
Based on 1 Customer Validation
BF-168, a candidate probe for PET, is found to specifically recognize both neuritic and diffuse plaques, with a Ki of 6.4 nM for Aβ1-42.
For research use only. We do not sell to patients.
- Purity: 99.68%
- CAS No.: 634911-47-0
- Formula: C18H17FN2O2
- Molecular Weight:312.34
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Storage:Powder -20°C, 3 years , 4°C, 2 years
* The compound is unstable in solutions, freshly prepared is recommended.
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Ki: 6.4 nM (Aβ1-42)[1].
BF-168, a styrylbenzoxazole derivative, is a potent agent that selectively recognizes SPs and NFTs in AD brain. BF-168 is a candidate probe for PET and is found to specifically recognize both neuritic and diffuse plaques, with a Ki of 6.4 nM for Aβ1-42[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 634911-47-0
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Appearance Solid
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Molecular Weight 312.34
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Formula C18H17FN2O2
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Color White to yellow
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SMILES
CNC1=CC=C(/C=C/C2=NC3=CC=C(OCCF)C=C3O2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years * The compound is unstable in solutions, freshly prepared is recommended.
Solvent & Solubility
DMSO : 50 mg/mL (160.08 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. The compound is unstable in solutions, freshly prepared is recommended.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.2016 mL | 16.0082 mL | 32.0164 mL | 80.0410 mL |
| 5 mM | 0.6403 mL | 3.2016 mL | 6.4033 mL | 16.0082 mL | |
| 10 mM | 0.3202 mL | 1.6008 mL | 3.2016 mL | 8.0041 mL | |
| 15 mM | 0.2134 mL | 1.0672 mL | 2.1344 mL | 5.3361 mL | |
| 20 mM | 0.1601 mL | 0.8004 mL | 1.6008 mL | 4.0020 mL | |
| 25 mM | 0.1281 mL | 0.6403 mL | 1.2807 mL | 3.2016 mL | |
| 30 mM | 0.1067 mL | 0.5336 mL | 1.0672 mL | 2.6680 mL | |
| 40 mM | 0.0800 mL | 0.4002 mL | 0.8004 mL | 2.0010 mL | |
| 50 mM | 0.0640 mL | 0.3202 mL | 0.6403 mL | 1.6008 mL | |
| 60 mM | 0.0534 mL | 0.2668 mL | 0.5336 mL | 1.3340 mL | |
| 80 mM | 0.0400 mL | 0.2001 mL | 0.4002 mL | 1.0005 mL | |
| 100 mM | 0.0320 mL | 0.1601 mL | 0.3202 mL | 0.8004 mL |
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