13 Results for "

Anti-CD47

" in MedChemExpress (MCE) Product Catalog:
Products (13)

13 Results for "Anti-CD47" in MCE Product Catalog:

4
Magrolimab
Magrolimab
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4 Cited Publications
Referencia número: HY-P99029
No. CAS: 2169232-81-7
Synonyms: Hu5F9-G4

Target:  

CD47

Áreas de investigación:  

Cancer

Magrolimab (Hu5F9-G4) is a humanized anti-CD47 antibody. Magrolimab, an IgG4 isotype, lacks ADCC function and exhibits relatively weak ADCP effector function. Magrolimab can be used for the study of malignant bone tumors and breast cancer .
1
Ligufalimab
Ligufalimab
0 Images
1 Cited Publications
Referencia número: HY-P99706
No. CAS: 2428381-55-7
Synonyms: AK 117

Target:  

CD47 Interleukin Related

Áreas de investigación:  

Cancer

Ligufalimab (AK 117) is a humanized IgG4 anti-CD47 monoclonal antibody. Ligufalimab does not induce RBC hemagglutination, and induces phagocytosis. Ligufalimab shows anti-tumor activity .
1
Urabrelimab
Urabrelimab
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1 Cited Publications
Referencia número: HY-P99533
No. CAS: 2249722-58-3
Synonyms: SRF-231; SRF231

Target:  

CD47 Interleukin Related

Áreas de investigación:  

Cancer

Urabrelimab (SRF231) is a fully human anti-CD47 monoclonal antibody that blocks the CD47-SIRP interaction .
1
Lemzoparlimab
Lemzoparlimab
0 Images
1 Cited Publications
Referencia número: HY-P99026
No. CAS: 2377483-71-9
Synonyms: TJ011133; TJC4

Target:  

CD47

Áreas de investigación:  

Cancer

Lemzoparlimab (TJ011133; TJC4) is a humanized anti-CD47 IgG4 antibody. Lemzoparlimab has a strong anti-tumor activity .
1
Letaplimab
Letaplimab
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1 Cited Publications
Referencia número: HY-P99700
No. CAS: 2283356-07-8
Synonyms: IBI-188

Target:  

Inhibitory Antibodies

Áreas de investigación:  

Cancer

Letaplimab (IBI-188) is a human IgG4 anti-CD47 monoclonal antibody. CD47 is overexpressed on cancer cells, it is a ligand for SIRPα. Letaplimab enhances tumor cell phagocytosis .
Anti-CD47 Antibody (B6.H12)
Anti-CD47 Antibody (B6.H12)
0 Images
Referencia número: HY-P990858

Target:  

CD47

Áreas de investigación:  

Cancer

Anti-CD47 Antibody (B6.H12) is a kind of mouse IgG1 κ chimeric antibody, targeting to human CD47. Anti-CD47 Antibody (B6.H12) blocks CD47 interactions with SIRPα. Anti-CD47 Antibody (B6.H12) inhibits cell proliferation, cell migration and invasion. Anti-CD47 Antibody (B6.H12) increases macrophage phagocytosis. Anti-CD47 Antibody (B6.H12) shows potent anti-tumor effect in various tumor models, such as osteosarcoma .
CC-90002
CC-90002
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Referencia número: HY-P99172
No. CAS: 2085844-54-6

Target:  

CD47 Interleukin Related

Áreas de investigación:  

Cancer

CC-90002 is a humanized anti-CD47 monoclonal antibody (mAb). CC-90002 has a high affinity for binding to CD47 with a subnanomolar Kd value. CC-90002 can be used for the research of hematologic malignancies and solid tumors .
Anti-CD47 Antibody (1F80)
Anti-CD47 Antibody (1F80)
0 Images
Referencia número: HY-P991923

Target:  

CD47

Áreas de investigación:  

Cancer

Anti-CD47 Antibody (1F80) is an antibody against human CD47. Recommend Isotype Controls:?Human IgG4 (S228P) kappa, Isotype Control (HY-P99003).
AO-176
AO-176
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Referencia número: HY-P991561
No. CAS: 2691109-74-5

Target:  

CD47

Áreas de investigación:  

Cancer

AO-176 is a humanized anti-CD47 IgG2 monoclonal antibody. AO-176 induces tumor phagocytosis through blocking the CD47-SIRPα interaction. AO-176 preferentially binds to tumor versus normal cells and directly kills tumor by a cell autonomous mechanism not ADCC (antibody-dependent cell-mediated cytotoxicity). AO-176 demonstrates dose-dependent antitumor activity in tumor xenograft models. AO-176 can be used for the researches of cancer, such as lymphoma .
VxP037
VxP037
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Referencia número: HY-P991926

Target:  

CD47

Áreas de investigación:  

Inflammation/Immunology

VxP037 is a humanized anti-CD47 antibody. The isotype control for VxP037 is Human IgG1 kappa, Isotype Control (HY-P99001) .
SHR-1603
SHR-1603
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Referencia número: HY-P991925

Target:  

CD47

Áreas de investigación:  

Cancer

SHR-1603 is a humanized anti-CD47 IgG4 antibody. SHR-1603 blocks the interaction of CD47 with SIRPα and enhances phagocytosis. SHR-1603 includes active Fc domains to mediate CDC/ADCC functions. SHR-1603 can be used for the research of cancer [1][2].
CO-1
CO-1
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Referencia número: HY-P991924

Target:  

CD47

Áreas de investigación:  

Cancer

CO-1 is an IgG4 anti-CD47 antibody. CO-1 not only enhances themacrophage phagocytosis activity but also induces a unique and fast form of programmed celldeath (PCD) in cancer cells directly through ligation of CD47. CO-1 has anticancer activity against hematologic malignancies such as acute lymphoblastic leukemia .
ZL-1201
ZL-1201
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Referencia número: HY-P991927

Target:  

CD47

Áreas de investigación:  

Cancer

ZL-1201 is a recombinant humanized monoclonal anti-CD47 IgG4 antibody. ZL-1201 disrupt the CD47-SIRPα interaction. ZL-1201 modulates the tumor microenvironment. ZL-1201 promotes tumor-associated macrophage phagocytic activity. ZL-1201 substantially enhances phagocytosis by M2 macrophages, but not by M1 macrophages. ZL-1201 in combination with both mAb and chemotherapy achieves the maximal antitumor effects in a variety of solid tumor models. ZL-1201 can be used in the study of lymphoma, breast cancer, ovarian cancer, head and neck squamous cell carcinoma, and gastric cancer .
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