7 Results for "

Iron+oxide

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Iron+oxide" in MCE Product Catalog:

Cat. No.: HY-108894
CAS No.: 722492-56-0
Purity:  95.00%
Ferumoxytol is an FDA-approved ultrasmall superparamagnetic iron oxide preparation and iron replacement agent that exerts selective activity against leukemia cells with low ferroportin expression. Ferumoxytol increases intracellular iron levels, induces reactive oxygen species (ROS) production via the Fenton reaction, and triggers oxidative stress and cell death. Ferumoxytol reduces disease burden in mouse models and patient-derived leukemia models. As an MRI contrast agent, Ferumoxytol enables imaging of vascular lesions, tumors and lymph nodes. Ferumoxytol can be used in research related to acute myeloid leukemia and blast-phase chronic myeloid leukemia .
Cat. No.: HY-164071
CAS No.: 9044-05-7
Synonyms: CM-Dextran
Target:  

Drug Derivative

Research Areas:  

Others

Carboxymethyl Dextran (CM-Dextran) is a dextran derivative and a biocompatible coating for superparamagnetic iron oxide nanoparticles. When coated on the surface of superparamagnetic nanoparticles, Carboxymethyl Dextran forms stable particles across all pH values and NaCl concentrations. Carboxymethyl Dextran can be used to prepare materials for magnetic resonance molecular imaging .
Cat. No.: HY-177205
DSPE-PEG2000-CRPPR is a polyethylene glycol (PEG) conjugate composed of DSPE and Heart-homing peptide (CRPPR) (HY-P10641). DSPE-PEGs are modified with the CRPPR peptide to bind cysteine-rich protein 2 (CRIP2) as well as FITC-labeled superparamagnetic iron oxide nanoparticles .
Cat. No.: HY-P10786
CAS No.: 2031154-77-3
Research Areas:  

Cancer

LinTT1 peptide is a tumor-penetrating peptide with the amino acid sequence AKRGARST. LinTT1 peptide targets peritoneal carcinoma (PC) by binding to the p32 (gC1qR) receptor. It can conjugate with iron oxide nanoworms (NWs) to form a nanocarrier. This nanocarrier is taken up by peritoneal carcinoma cells in vitro and enters the mitochondria; it also exhibits significant tumor targeting and penetration effects in mice. Moreover, LinTT1-functionalized nanocarriers, combined with the pro-apoptotic peptide [D(KLAKLAK)2], show significant tumor suppression in a mouse peritoneal tumor model. LinTT1 peptide holds promise as a delivery carrier for peritoneal cancer research .
Cat. No.: HY-153217
CAS No.: 36465-76-6
Research Areas:  

Others

Arsonic acid is a robust anchor group for the surface modification of Fe3O4. Arsonic acid binds strongly to the surface of iron oxide nanoparticles .
Cat. No.: HY-174906A
Research Areas:  

Others

Bis-PEG2000-COOH is a dicarboxyl-terminated polyethylene glycol and surface modification reagent with hydrophilic, biocompatible properties. Bis-PEG2000-COOH coats superparamagnetic iron oxide nanoparticles to prepare carriers for conjugating antigen p210 and adjuvant CpG oligodeoxynucleotides in nanovaccine formulation .
Cat. No.: HY-P11887
CAS No.: 1174559-81-9
VHPKQHR is a peptide-based delivery enhancer that binds to VCAM-1. VHPKQHR enables intracellular internalization of relevant nanomaterials and facilitates the targeted delivery of miRNA inhibitors to inflamed endothelial cells and endothelial cells activated by disturbed flow. When conjugated with magnetic mesoporous silica nanoparticles, VHPKQHR achieves targeted accumulation at atherosclerotic plaque sites. When displayed on the surface of polyelectrolyte complex micelles, VHPKQHR enhances the relevant effects of anti-miR-92a in Apoe -/- mice. When conjugated with ultrasmall superparamagnetic iron oxide nanoparticles, VHPKQHR forms a contrast agent for T1-weighted magnetic resonance imaging. VHPKQHR can be used in research related to atherosclerosis, stenosis and rheumatoid arthritis .