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Cat. No.: HY-174906A

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Bis-PEG2000-COOH

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Based on 1 Customer Validation

Bis-PEG2000-COOH is a dicarboxyl-terminated polyethylene glycol and surface modification reagent with hydrophilic, biocompatible properties. Bis-PEG2000-COOH coats superparamagnetic iron oxide nanoparticles to prepare carriers for conjugating antigen p210 and adjuvant CpG oligodeoxynucleotides in nanovaccine formulation.

For research use only. We do not sell to patients.

Molecular Weight:2000 (Average)

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Bis-PEG2000-COOH Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Solvent & Solubility
- In Vitro
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

In Vitro

Bis-PEG2000-COOH (60 mg; 12 h) successfully modifies Fe₃O₄@OA nanoparticles to form Fe₃O₄@DA-PEG^[1].
Bis-PEG2000-COOH (100 mg; 24 h) successfully grafts to amino-functionalized SED-150 long afterglow nanospheres^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Appearance Powder
Molecular Weight 2000 (Average)
SMILES

OC(CCOCCC(O)=O)=O.[n]
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Fernandes S, et al. Magnetic Nanoparticle-Based Hyperthermia Mediates Drug Delivery and Impairs the Tumorigenic Capacity of Quiescent Colorectal Cancer Stem Cells. ACS Appl Mater Interfaces. 2021 Apr 14;13(14):15959-15972. [Content Brief]

[2]. Li ZJ, et al. A facile and effective method to prepare long-persistent phosphorescent nanospheres and its potential application for in vivo imaging. J. Master. Chem. 2012 Oct 4;22:24713.

[3]. Zhang L, et al. A nanovaccine for immune activation and prophylactic protection of atherosclerosis in mouse models. Nat Commun. 2025;16(1):2111. Published 2025 Mar 2. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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