Bis-PEG2000-COOH
Based on 1 Customer Validation
Bis-PEG2000-COOH is a dicarboxyl-terminated polyethylene glycol and surface modification reagent with hydrophilic, biocompatible properties. Bis-PEG2000-COOH coats superparamagnetic iron oxide nanoparticles to prepare carriers for conjugating antigen p210 and adjuvant CpG oligodeoxynucleotides in nanovaccine formulation.
For research use only. We do not sell to patients.
- Molecular Weight:2000 (Average)
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Bis-PEG2000-COOH (60 mg; 12 h) successfully modifies Fe3O4@OA nanoparticles to form Fe3O4@DA-PEG[1].
Bis-PEG2000-COOH (100 mg; 24 h) successfully grafts to amino-functionalized SED-150 long afterglow nanospheres[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Appearance Powder
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Molecular Weight 2000 (Average)
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SMILES
OC(CCOCCC(O)=O)=O.[n]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
Purity & Documentation
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Data Sheet (266 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Fernandes S, et al. Magnetic Nanoparticle-Based Hyperthermia Mediates Drug Delivery and Impairs the Tumorigenic Capacity of Quiescent Colorectal Cancer Stem Cells. ACS Appl Mater Interfaces. 2021 Apr 14;13(14):15959-15972. [Content Brief]
[3]. Zhang L, et al. A nanovaccine for immune activation and prophylactic protection of atherosclerosis in mouse models. Nat Commun. 2025;16(1):2111. Published 2025 Mar 2. [Content Brief]
Bis-PEG2000-COOH Related Classifications
HY-174906A Related Classifications
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