7 Results for "

Nav1.9

" in MedChemExpress (MCE) Product Catalog:
Products (7)

7 Results for "Nav1.9" in MCE Product Catalog:

  • Isoforms Recommended:
DSP-2230
DSP-2230
0 Images
Cat. No.: HY-125079
CAS No.: 1233231-30-5
Pureté:  98.33%
Synonyms: ANP-230
Target:  

Sodium Channel

Domaines de recherche:  

Cardiovascular Disease Neurological Disease

DSP-2230 is the orally active inhibitor for voltage-gated sodium channel that inhibits Nav1.7-, Nav1.8-, and Nav1.9-derived sodium currents with IC50s of 7.1 μM, 11.4 μM and 6.7 μM, respectively. DSP-2230 can be used to improve neuropathic pain .
LTGO-33
LTGO-33
0 Images
Cat. No.: HY-157802
CAS No.: 2834106-06-6
Pureté:  99.35%
Target:  

Sodium Channel

Domaines de recherche:  

Neurological Disease

LTGO-33 is a potent and selective voltage-gated sodium channel NaV1.8 inhibitor. LTGO-33 inhibits NaV1.8 in the nM potency range and exhibits over 600-fold selectivity against human NaV1.1-NaV1.7 and NaV1.9. LTGO-33 exhibits state-independent inhibition with similar potencies on channels in the closed and inactivated conformations. LTGO-33 inhibits native TTX-R NaV1.8 currents in non-human primate and human DRG neurons, where it reduces action potential firing. LTGO-33 can be used for pain disorders research .
E0199
E0199
0 Images
Cat. No.: HY-178281
CAS No.: 931928-13-1
Target:  

Potassium Channel Sodium Channel

Domaines de recherche:  

Neurological Disease

E0199 is a novel potent dual-target KV7/NaV modulator that activates the KV7 channel (KV7.2/7.3 (EC50 = 12.78 nM), KV7.2 (EC50 = 0.50 μM), and KV7.5 (EC50 = 27.14 nM) channels) while simultaneously blocks the NaV1.7 (IC50 = 0.52 μM), NaV1.8 (IC50 = 0.24 μM), and NaV1.9 (IC50 = 0.16 μM) channels. E0199 shows a potent analgesic effect without affecting heart and skeletal muscle ion channels critically in a chronic constriction injury (CCI) mouse model. E0199 can be used for Neuropathic pain (NP) research .
Heteropodatoxin-1
Heteropodatoxin-1
0 Images
Cat. No.: HY-P5786
Synonyms: HpTx1
Target:  

Potassium Channel Sodium Channel

Domaines de recherche:  

Neurological Disease

Heteropodatoxin-1 (HpTx1), a spider peptide toxin, is a Kv4.2 current inhibitor. Heteropodatoxin-1 also inhibits Nav1.7 and activates Nav1.9 but does not affect Nav1.8 .
Anti-SCN11a/Nav1.9 Antibody
Anti-SCN11a/Nav1.9 Antibody
0 Images
Cat. No.: HY-P990502

Target:  

Sodium Channel

Domaines de recherche:  

Inflammation/Immunology

The Anti-SCN11a/Nav1.9 Antibody is a CHO-expressed human antibody that targets SCN11a/Nav1.9. The Anti-SCN11a/Nav1.9 Antibody features a huIgG1 heavy chain and a huκ light chain, with a predicted molecular weight (MW) of 143.94 kDa. The isotype control for the Anti-SCN11a/Nav1.9 Antibody can be referenced as Human IgG1 kappa, Isotype Control (HY-P99001).
Scn11a Mouse Pre-designed siRNA Set A
Scn11a Mouse Pre-designed siRNA Set A
Cat. No.: HY-RS12523
Target:  

Small Interfering RNA (siRNA)

Domaines de recherche:  

Others

Scn11a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Scn11a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.

SCN11A Human Pre-designed siRNA Set A
SCN11A Human Pre-designed siRNA Set A
Cat. No.: HY-RS12522
Target:  

Small Interfering RNA (siRNA)

Domaines de recherche:  

Others

SCN11A Human Pre-designed siRNA Set A contains three designed siRNAs for SCN11A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.

Assay Types