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Referencia número: HY-P5786

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Heteropodatoxin-1

Name: Heteropodatoxin-1
Brand: MedChemExpress
SKU: HY-P5786
Availability: PreOrder

(Synonyms: HpTx1)

Heteropodatoxin-1 (HpTx1), a spider peptide toxin, is a Kv4.2 current inhibitor. Heteropodatoxin-1 also inhibits Nav1.7 and activates Nav1.9 but does not affect Nav1.8.

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Fòrmula: C₁₆₈H₂₃₈N₄₆O₅₁S₆
Peso molecular:3910.35

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Heteropodatoxin-1 Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

Heteropodatoxin-1 (HpTx1), a spider peptide toxin, is a Kv4.2 current inhibitor. Heteropodatoxin-1 also inhibits Nav1.7 and activates Nav1.9 but does not affect Nav1.8^[1].

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Chemical Information

Peso molecular 3910.35
Fòrmula C₁₆₈H₂₃₈N₄₆O₅₁S₆
Synonyms

HpTx1
Sequence

Asp-Cys-Gly-Thr-Ile-Trp-His-Tyr-Cys-Gly-Thr-Asp-Gln-Ser-Glu-Cys-Cys-Glu-Gly-Trp-Lys-Cys-Ser-Arg-Gln-Leu-Cys-Lys-Tyr-Val-Ile-Asp-Trp-NH2 (Disulfide bridge:Cys2-Cys17;Cys9-Cys22;Cys16-Cys27)
Sequence Shortening

DCGTIWHYCGTDQSECCEGWKCSRQLCKYVIDW-NH2 (Disulfide bridge:Cys2-Cys17;Cys9-Cys22;Cys16-Cys27)
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (258 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Xi Zhou, et al. Spider venom-derived peptide induces hyperalgesia in Nav1.7 knockout mice by activating Nav1.9 channels. Nat Commun. 2020 May 8;11(1):2293. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Heteropodatoxin-1

Ver todos los productos específicos de isoformas Sodium Channel

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

Heteropodatoxin-1 Related Classifications

HY-P5786 Related Classifications

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