2. Membrane Transporter/Ion Channel
  3. Potassium Channel Sodium Channel
  4. Heteropodatoxin-1

Heteropodatoxin-1 (HpTx1), a spider peptide toxin, is a Kv4.2 current inhibitor. Heteropodatoxin-1 also inhibits Nav1.7 and activates Nav1.9 but does not affect Nav1.8.

For research use only. We do not sell to patients.

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Heteropodatoxin-1 Chemical Structure

Heteropodatoxin-1 Chemical Structure

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Heteropodatoxin-1 Related Antibodies

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Description

Heteropodatoxin-1 (HpTx1), a spider peptide toxin, is a Kv4.2 current inhibitor. Heteropodatoxin-1 also inhibits Nav1.7 and activates Nav1.9 but does not affect Nav1.8[1].

Molecular Weight

3910.35

Formula

C168H238N46O51S6
Sequence

Asp-Cys-Gly-Thr-Ile-Trp-His-Tyr-Cys-Gly-Thr-Asp-Gln-Ser-Glu-Cys-Cys-Glu-Gly-Trp-Lys-Cys-Ser-Arg-Gln-Leu-Cys-Lys-Tyr-Val-Ile-Asp-Trp-NH2 (Disulfide bridge:Cys2-Cys17;Cys9-Cys22;Cys16-Cys27)
Sequence Shortening

DCGTIWHYCGTDQSECCEGWKCSRQLCKYVIDW-NH2 (Disulfide bridge:Cys2-Cys17;Cys9-Cys22;Cys16-Cys27)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Heteropodatoxin-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Heteropodatoxin-1Heteropodatoxin1Heteropodatoxin 1Potassium ChannelSodium ChannelKcsANa channelsNa+ channelsKv4.2 InhibitorNav1.7 InhibitorNav1.9 Activatorspider peptide toxinInhibitorinhibitorinhibit

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