4 Results for "

small+RNA

" in MedChemExpress (MCE) Product Catalog:
Products (4)

4 Results for "small+RNA" in MCE Product Catalog:

2
4A3-SC8
4A3-SC8
0 Images
2 Cited Publications
Cat. No.: HY-148559
CAS No.: 1857340-78-3
Purity:  99.21%
Target:  

Liposome

Research Areas:  

Cancer

4A3-SC8 is a modular degradable dendrimer that enables small RNAs to extend survival in an aggressive liver cancer model .
1
5A2-SC8
5A2-SC8
0 Images
1 Cited Publications
Cat. No.: HY-145799
CAS No.: 1857341-90-2
Purity:  95.98%
5A2-SC8 is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
1
5A2-SC8 TFA
5A2-SC8 TFA
0 Images
1 Cited Publications
Cat. No.: HY-145799A
Purity:  98.03%
Target:  

Liposome

Research Areas:  

Cancer

5A2-SC8 TFA is an ionizable amino lipid in lipid nanoparticles (LNPs) that shows high delivery potential and low in vivo toxicity, enabling efficient delivery of small RNAs such as siRNA and miRNA into tumor cells. 5A2-SC8 TFA LNPs can confer a unique delivery fate of RNA within the liver, thereby changing the therapeutic outcomes in cancer models .
Trioxacarcin B
Trioxacarcin B
0 Images
Cat. No.: HY-126929
CAS No.: 81534-36-3
Synonyms: TXN-B
Target:  

DNA Alkylator/Crosslinker Apoptosis Bacterial Parasite Fungal

Research Areas:  

Infection Cancer

Trioxacarcin B (TXN-B) is a potent cytotoxic agent and DNA-targeted inhibitor. Trioxacarcin B disrupts DNA function and induces apoptosis in cancer cells. Trioxacarcin B not only effectively inhibits the growth of various Gram-positive and Gram-negative bacteria as well as Plasmodium falciparum, but also blocks the colony formation of cancer stem cells, significantly reduces tumor volume and prolongs survival in preclinical in vivo models. The activity of Trioxacarcin B is highly dependent on its intact spiro-epoxide structure; it loses efficacy once this moiety undergoes hydrolysis, and Trioxacarcin B shows no activity against fungi, microalgae and small RNA viruses. Trioxacarcin B can be used for research on bacterial infections, malaria, and various cancers including colon cancer and melanoma .
Assay Types