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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
19 Results for "
Cabozantinib-S-
" in MedChemExpress (MCE) Product Catalog:
Products (19)
19 Results for "Cabozantinib-S-" in MCE Product Catalog:
58
58 Publications Verification
Synonyms: XL184; BMS-907351
Target:
Research Areas:
Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035, and 1.3 nM, respectively. Cabozantinib displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 (IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib shows antiangiogenic activity. Cabozantinib disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis .
57
57 Cited Publications
Synonyms: XL184 S-malate; BMS-907351 S-malate
Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
Synonyms: XL184-d6; BMS-907351-d6
Cat. No.: HY-13016R
CAS No.: 849217-68-1
Synonyms: XL184 (Standard); BMS-907351 (Standard)
Research Areas:
Cabozantinib (Standard) is the analytical standard of Cabozantinib. This product is intended for research and analytical applications. Cabozantinib is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035, and 1.3 nM, respectively. Cabozantinib displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 (IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib shows antiangiogenic activity. Cabozantinib disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis .
Cat. No.: HY-13016S1
CAS No.: 1802168-53-1
Synonyms: XL184-d4; BMS-907351-d4
Cat. No.: HY-13016A
CAS No.: 1817759-42-4
Synonyms: XL184 hydrochloride; BMS-907351 hydrochloride
Target:
Research Areas:
Cabozantinib hydrochloride is a potent and orally active inhibitor of VEGFR2 and MET, with IC50 values of 0.035 and 1.3 nM, respectively. Cabozantinib hydrochloride displays strong inhibition of KIT, RET, AXL, TIE2, and FLT3 (IC50=4.6, 5.2, 7, 14.3, and 11.3 nM, respectively). Cabozantinib hydrochloride shows antiangiogenic activity. Cabozantinib hydrochloride disrupts tumor vasculature and promotes tumor and endothelial cell apoptosis .
Cat. No.: HY-45124
CAS No.: 849217-50-1
Research Areas:
3-Fluoro-desmethyl-cabozantinib is an BCL6 ligand that can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961) . 3-Fluoro-desmethyl-cabozantinib is also a p38α ligand that can be used to synthesize PROTACs, such as SJFα (HY-114404) .
Cat. No.: HY-109084A
Synonyms: CT-707 tetrahydrochloride
Conteltinib tetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride salt form of Conteltinib (HY-109084). Conteltinib tetrahydrochloride is the inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. Conteltinib tetrahydrochloride exhibits a synergistic anti-tumor efficacy with Cabozantinib (HY-13016) .
Cat. No.: HY-12044R
CAS No.: 1140909-48-3
Synonyms: XL184 S-malate (Standard); BMS-907351 S-malate (Standard)
Target:
Research Areas:
Cabozantinib (S-malate) (Standard) is the analytical standard of Cabozantinib (S-malate). This product is intended for research and analytical applications. Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
Cat. No.: HY-176385
CAS No.: 2230826-10-3
Research Areas:
3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid is a target protein ligand-linker conjugate that incorporates a ligand for c-Met (HY-451241) and a PROTAC linker (HY-W442078), which recruits E3 ligases. 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961) .
Cat. No.: HY-100833R
CAS No.: 251349-54-9
Target:
Research Areas:
Cabozantinib (S-malate) (Standard) is the analytical standard of Cabozantinib (S-malate). This product is intended for research and analytical applications. Cabozantinib S-malate (XL184 S-malate) is a potent multiple receptor tyrosine kinases inhibitor that inhibits VEGFR2, c-Met, Kit, Axl and Flt3 with IC50s of 0.035, 1.3, 4.6, 7 and 11.3 nM, respectively.
Cat. No.: HY-10338A
CAS No.: 1226999-07-0
Target:
Research Areas:
Foretinib phosphate is an orally bioavailable small molecule with potential anti-tumor activity. Foretinib phosphate can selectively inhibit hepatocyte growth factor (HGF) receptor c-MET and vascular endothelial growth factor receptor 2 (VEGFR2), thereby potentially inhibiting tumor angiogenesis, tumor cell proliferation and metastasis. Foretinib phosphate shows different anti-cancer activity from cabozantinib in lung cancer cells and has stronger inhibitory effects on targets such as MEK1/2, FER and AURKB .
Cat. No.: HY-W706452
Synonyms: XL184-d4 S-malate; BMS-907351-d4 S-malate
Cat. No.: HY-Z1053
CAS No.: 748707-58-6
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Cabozantinib impurity 8 is an impurity of Cabozantinib (HY-13016).
Cat. No.: HY-Z2093
CAS No.: 1247859-37-5
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Research Areas:
Cabozantinib impurity 7 is an impurity of Cabozantinib (HY-13016).
Cat. No.: HY-Z2199
CAS No.: 918642-61-2
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Research Areas:
Cabozantinib impurity 1 is an impurity of Cabozantinib (HY-13016).
Cat. No.: HY-Z1053R
CAS No.: 748707-58-6
Target:
Research Areas:
Cabozantinib impurity 8 (Standard) is the analytical standard of Cabozantinib impurity 8 (HY-Z1053). This product is intended for research and analytical applications.
Cat. No.: HY-Z2093R
CAS No.: 1247859-37-5
Target:
1-((3-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid (Cabozantinib Impurity) (Standard) is the analytical standard of 1-((3-Fluorophenyl)carbamoyl)cyclopropanecarboxylic acid (Cabozantinib Impurity). This product is intended for research and analytical applications.
Cat. No.: HY-Z2199R
CAS No.: 918642-61-2
Target:
1-((2-fluorophenyl)carbamoyl)cyclopropanecarboxylic acid (Cabozantinib Impurity） (Standard) is the analytical standard of 1-((2-fluorophenyl)carbamoyl)cyclopropanecarboxylic acid (Cabozantinib Impurity）. This product is intended for research and analytical applications.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
