Conteltinib tetrahydrochloride
Based on 1 Customer Validation
Conteltinib tetrahydrochloride (CT-707 tetrahydrochloride) is the tetrahydrochloride salt form of Conteltinib (HY-109084). Conteltinib tetrahydrochloride is the inhibitor for FAK (IC50=1.6 nM), ALK, and Pyk2. Conteltinib tetrahydrochloride exhibits a synergistic anti-tumor efficacy with Cabozantinib (HY-13016).
For research use only. We do not sell to patients.
- Purity: 99.60%
- Formula: C32H49Cl4N9O3S
- Molecular Weight:781.67
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Anti-Cancer Compound Library
HY-L025
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Clinical Compound Library
HY-L026
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Drug Repurposing Compound Library
HY-L035
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Cytoskeleton Compound Library
HY-L060
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Anti-Pancreatic Cancer Compound Library
HY-L077
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Anti-Pulmonary Fibrosis Compound Library
HY-L125
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MCE Bioactive Compound Library
HY-L001V
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Drug Repurposing Compound Library Plus
HY-L035P
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Clinical Compound Library Plus
HY-L026P
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
Biological Activity
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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Appearance Solid
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Molecular Weight 781.67
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Formula C32H49Cl4N9O3S
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Color Light yellow to yellow
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SMILES
O=S(NC(C)C)(C1=C(NC2=NC(NC3=CC=C(N4CCC(CC4)N5CCN(CC5)C)C=C3OC)=NC6=C2CCN6)C=CC=C1)=O.Cl.Cl.Cl.Cl
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Synonyms
CT-707 tetrahydrochloride
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
DMSO : 100 mg/mL (127.93 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2793 mL | 6.3966 mL | 12.7931 mL | 31.9828 mL |
| 5 mM | 0.2559 mL | 1.2793 mL | 2.5586 mL | 6.3966 mL | |
| 10 mM | 0.1279 mL | 0.6397 mL | 1.2793 mL | 3.1983 mL | |
| 15 mM | 0.0853 mL | 0.4264 mL | 0.8529 mL | 2.1322 mL | |
| 20 mM | 0.0640 mL | 0.3198 mL | 0.6397 mL | 1.5991 mL | |
| 25 mM | 0.0512 mL | 0.2559 mL | 0.5117 mL | 1.2793 mL | |
| 30 mM | 0.0426 mL | 0.2132 mL | 0.4264 mL | 1.0661 mL | |
| 40 mM | 0.0320 mL | 0.1599 mL | 0.3198 mL | 0.7996 mL | |
| 50 mM | 0.0256 mL | 0.1279 mL | 0.2559 mL | 0.6397 mL | |
| 60 mM | 0.0213 mL | 0.1066 mL | 0.2132 mL | 0.5330 mL | |
| 80 mM | 0.0160 mL | 0.0800 mL | 0.1599 mL | 0.3998 mL | |
| 100 mM | 0.0128 mL | 0.0640 mL | 0.1279 mL | 0.3198 mL |
Conteltinib tetrahydrochloride Related Classifications
HY-109084A Related Classifications
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