2230826-10-3
2230826-10-3
Chemical Structure
3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid
- CAS No.: 2230826-10-3
- Formula:C36H37F2N3O9
- Molecular Weight:693.69
SMILES: FC1=CC=C(C=C1)NC(C2(C(NC3=CC(F)=C(C=C3)OC4=CC=NC5=C4C=C(C(OCCCOCCCOCCC(O)=O)=C5)OC)=O)CC2)=O
Biological Activity: 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid is a target protein ligand-linker conjugate that incorporates a ligand for c-Met (HY-451241) and a PROTAC linker (HY-W442078), which recruits E3 ligases. 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961)[1].
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3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid | 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid is a target protein ligand-linker conjugate that incorporates a ligand for c-Met (HY-451241) and a PROTAC linker (HY-W442078), which recruits E3 ligases. 3-Fluoro-desmethyl-cabozantinib-C3-O-C3-PEG-acid can be used in the synthesis of PROTACs, such as SJF-8240 (HY-123961). | |||||||||||||||||||||
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