6 Results for "

Gedatolisib

" in MedChemExpress (MCE) Product Catalog:
Products (6)

6 Results for "Gedatolisib" in MCE Product Catalog:

6
Gedatolisib
Gedatolisib
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6 Cited Publications
Cat. No.: HY-10681
CAS No.: 1197160-78-3
Purity:  99.68%
Synonyms: PKI-587; PF-05212384
Target:  

PI3K mTOR

Research Areas:  

Cancer

Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0.4 nM, 5.4 nM and 1.6 nM, respectively . Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2 .
Gedatolisib (Standard)
Gedatolisib (Standard)
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Cat. No.: HY-10681R
CAS No.: 1197160-78-3
Target:  

PI3K mTOR Reference Standards

Research Areas:  

Cancer

Gedatolisib (Standard) is the analytical standard of Gedatolisib. This product is intended for research and analytical applications. Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0.4 nM, 5.4 nM and 1.6 nM, respectively . Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2 .
PI3K/mTOR Inhibitor-7
PI3K/mTOR Inhibitor-7
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Cat. No.: HY-147614
CAS No.: 2456295-65-9
Target:  

PI3K mTOR

Research Areas:  

Cancer

PI3K/mTOR Inhibitor-7 (Compound 19i) is a potent and dual inhibitor of PI3K/mTOR. PI3K/mTOR Inhibitor-7 shows 4.7-fold higher potency than the positive control gedatolisib (0.3 vs. 1.4 μM, IC50 values). PI3K/mTOR Inhibitor-7 significantly suppresses the PI3K/Akt/mTOR signaling pathway at 10 μM. PI3K/mTOR Inhibitor-7 has the potential for the research of cancer diseases .
PI3K/mTOR Inhibitor-6
PI3K/mTOR Inhibitor-6
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Cat. No.: HY-147613
CAS No.: 2456295-59-1
Target:  

PI3K mTOR

Research Areas:  

Cancer

PI3K/mTOR Inhibitor-6 (Compound 19c) is a potent and dual inhibitor of PI3K/mTOR. PI3K/mTOR Inhibitor-6 displays better stability in artificial gastric fluids than gedatolisib. PI3K/mTOR Inhibitor-6 significantly suppresses the PI3K/Akt/mTOR signaling pathway at 10 μM. PI3K/mTOR Inhibitor-6 has the potential for the research of cancer diseases .
Gedatolisib-d8
Gedatolisib-d8
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Cat. No.: HY-10681S
Synonyms: PKI-587-d8; PF-05212384-d8
Gedatolisib-d8 (PKI-587-d8) is the deuterium labeled Gedatolisib (HY-10681). Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0.4 nM, 5.4 nM and 1.6 nM, respectively. Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2 .
Gedatolisib-d6
Gedatolisib-d6
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Cat. No.: HY-10681S1
Synonyms: PKI-587-d6; PF-05212384-d6
Gedatolisib-d6 (PKI-587-d6) is the deuterium labeled Gedatolisib (HY-10681). Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0.4 nM, 5.4 nM and 1.6 nM, respectively . Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2 .
Assay Types