DOTAM-NHS-ester
DOTAM-NHS-ester is a bifunctional chelator and a macrocyclic DOTA derivative used for tumor pre-targeting. DOTAM-NHS-ester combines the efficient metal chelating ability of DOTAM macrocyclic ligands with the bioconjugation function of NHS ester active groups, and can be widely used in the biomedical field for metal labeling, molecular imaging and drug delivery development.
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- CAS. Nr.: 2236057-47-7
- Formel: C20H34N8O7
- Molecular Weight:498.53
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Speicherung:
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
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Biologische Aktivität
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RDC Bifunctional Chelator |
DOTAM-NHS ester (composed of DOTAM and NHS ester) is a chelator that forms stable complexes with various metal ions and reacts with amino groups to form stable amide bonds; it is used as a biomolecule labeling reagent to introduce DOTAM into biomolecules for localization and tracking, applied to prepare metal ion-labeled probes for bioimaging, and serves as a contrast agent to improve imaging contrast and resolution by binding to specific biomolecules[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 2236057-47-7
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Appearance Solid
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Molecular Weight 498.53
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Formel C20H34N8O7
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Color White to off-white
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SMILES
O=C(ON1C(CCC1=O)=O)CN2CCN(CC(N)=O)CCN(CC(N)=O)CCN(CC(N)=O)CC2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DOTAM-NHS-ester Related Classifications
HY-158072 Related Classifications
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