Reuterin
Based on 4 publication(s) in Google Scholar
Reuterin is a broad-spectrum antimicrobial agent active against Gram positive and Gram negative bacteria, as well as yeasts, moulds and protozoa. Reuterin is produced by specific strains of Lactobacillus reuteri during anaerobic metabolism of glycerol. Reuterin also demonstrates potent antimicrobial activity against a broad panel of human and poultry meat campylobacter spp. Isolates.
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- Reinheit: 98.45%
- CAS. Nr.: 2134-29-4
- Formel: C3H6O2
- Molecular Weight:74.08
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Speicherung:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Publications Citing Use of MedChemExpress (MCE) Reuterin
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Biologische Aktivität
Reuterin is water soluble, effective in a wide range of pH, resistant to proteolytic and lipolytic enzymes and has been therefore studied as a food preservative or auxiliary therapeutic agent. Reuterin is a potent antimicrobial with high activity against a broad panel of C. jejuni and C. coli isolates[1].
Reuterin is produced by certain strains of L. reuteri during anaerobic fermentation of glycerol and has a broad-spectrum antimicrobial property against enteric pathogens and intestinal bacteria[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS. Nr. 2134-29-4
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Appearance Liquid (Density: 1.016±0.06 g/cm3)
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Molecular Weight 74.08
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Formel C3H6O2
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Color Colorless to light yellow
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SMILES
O=CCCO
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Synonyms
3-Hydroxypropionaldehyde; 3-Hydroxypropanal
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Structure Classification
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Initial Source
Lactobacillus reuteri
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (4)
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Journal Impact Factor
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Most Recent
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Food Chem
Innovative bioproduction of natural food preservative 3-hydroxypropionaldehyde by evolved Limosilactobacillus reuteri NK45. [Abstract]2026 Mar 19:512:148955. PMID: 41880962 -
Int J Biol Macromol
Antibacterial reuterin as a multifunctional crosslinker for constructing chitosan-based hydrogels to promote infected wound healing. [Abstract]2025 May 24:144494. PMID: 40419054 -
Phytomedicine
3-Hydroxypropionaldehyde modulates tryptophan metabolism to activate AhR signaling and alleviate ethanol-induced liver injury. [Abstract]2025 Feb 2:139:156445. PMID: 39922148 -
Protein Sci
Engineering a self-organized enzyme cascade for enhanced cell-free biosynthesis of 3-hydroxypropionic acid. [Abstract]2026 Jun;35(6):e70598. PMID: 42080289
Lösungsmittel & Löslichkeit
H2O : ≥ 100 mg/mL (1349.89 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
For the following dissolution methods, please prepare the working solution directly:
It is recommended to prepare fresh solutions and use them promptly within a short period of time.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: PBS
Solubility: 100 mg/mL (1349.89 mM); Clear solution; Need ultrasonic
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Reinheit & Dokumentation
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Data Sheet (270 KB)
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SDS (396 KB)
- English - EN (396 KB)
- Français - FR (396 KB)
- Deutsch - DE (396 KB)
- Norwegian - NO (396 KB)
- Español - ES (396 KB)
- Swedish - SV (396 KB)
- Italian - IT (396 KB)
- Portuguese - PT (396 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Schaefer L, et al. The antimicrobial compound reuterin (3-hydroxypropionaldehyde) induces oxidative stress via interaction with thiol groups. Microbiology (Reading). 2010;156(Pt 6):1589-1599. [Content Brief]
[2]. Asare PT, et al. Reuterin Demonstrates Potent Antimicrobial Activity Against a Broad Panel of Human and Poultry Meat Campylobacter spp. Isolates. Microorganisms. 2020;8(1):78. Published 2020 Jan 6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 13.4989 mL | 67.4946 mL | 134.9892 mL | 337.4730 mL |
| 5 mM | 2.6998 mL | 13.4989 mL | 26.9978 mL | 67.4946 mL | |
| 10 mM | 1.3499 mL | 6.7495 mL | 13.4989 mL | 33.7473 mL | |
| 15 mM | 0.8999 mL | 4.4996 mL | 8.9993 mL | 22.4982 mL | |
| 20 mM | 0.6749 mL | 3.3747 mL | 6.7495 mL | 16.8736 mL | |
| 25 mM | 0.5400 mL | 2.6998 mL | 5.3996 mL | 13.4989 mL | |
| 30 mM | 0.4500 mL | 2.2498 mL | 4.4996 mL | 11.2491 mL | |
| 40 mM | 0.3375 mL | 1.6874 mL | 3.3747 mL | 8.4368 mL | |
| 50 mM | 0.2700 mL | 1.3499 mL | 2.6998 mL | 6.7495 mL | |
| 60 mM | 0.2250 mL | 1.1249 mL | 2.2498 mL | 5.6245 mL | |
| 80 mM | 0.1687 mL | 0.8437 mL | 1.6874 mL | 4.2184 mL | |
| 100 mM | 0.1350 mL | 0.6749 mL | 1.3499 mL | 3.3747 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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