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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
AP-3
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "AP-3" in MCE Product Catalog:
1
Category:
Human Gut Microbiota Metabolites Natural Products Microorganisms Neurological Disease Endogenous metabolite Disease Research Fields Cancer
Target:
Art. -Nr.: HY-19587
CAS. Nr.: 74517-42-3
Synonyms: NSC335153
Target:
Forschungsgebiete:
Ditercalinium chloride is an anticancer agent. Ditercalinium chloride inhibits human DNA polymerase gamma activity. Ditercalinium chloride can deplete mitochondrial DNA in both mouse and human cells. Ditercalinium chloride is a potential ligand against the COMMD10-AP3S1 fusion protein .
Art. -Nr.: HY-108546
CAS. Nr.: 23052-80-4
Synonyms: 3-Phosphono-L-alanine
Target:
Forschungsgebiete:
L-AP3, metabotropic glutamate receptor (mGluR) antagonist, inhibits D-phosphoserine and L-phosphoserine with IC50s of 368 μM and 2087 μM, respectively .
Target:
Forschungsgebiete:
Ap3A is a vasoactive molecule that regulates intracellular Ca 2+ levels. Ap3A can promote the growth of vascular smooth muscle cells .
Art. -Nr.: HY-139105
CAS. Nr.: 72902-38-6
Target:
20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic .
Art. -Nr.: HY-159857
Synonyms: Gp(2′-5′)AP(3′) sodium; 2'5'-GpAP sodium; Guanylyl-(2′→5′)-3′-adenylic acid sodium
Target:
Gp(2′-5′)Ap sodium is a linear dinucleotide analog after hydrolysis of cyclic guanosine monophosphate- adenosine monophosphate (2’3’-cGAMP) by phosphodiesterases. Due to its linear conformation, 2’5’GpAp is intended to serve as a negative control for 2’3’-cGAMP in type I IFN induction assays.
Art. -Nr.: HY-10082A
CAS. Nr.: 200933-27-3
Synonyms: (E)-PAN-811; (E)-NSC# 663249; (E)-OCX191
Target:
Forschungsgebiete:
(E)-3-AP is the E configuration of 3-AP. 3-AP is a potent ribonucleotide reductase inhibitor. 3-AP shows anti-proliferative activity. 3-AP shows anticancer activity in L1210 leukemia model. 3-AP inhibits RR activity and DNA synthesis .
Art. -Nr.: HY-RS00789
Target:
Forschungsgebiete:
AP3B1 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3B1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS00790
Target:
Forschungsgebiete:
AP3B2 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3B2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS00791
Target:
Forschungsgebiete:
AP3D1 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3D1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS00792
Target:
Forschungsgebiete:
AP3M1 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3M1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS00793
Target:
Forschungsgebiete:
AP3M2 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3M2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS00794
Target:
Forschungsgebiete:
AP3S1 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3S1 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RS00795
Target:
Forschungsgebiete:
AP3S2 Human Pre-designed siRNA Set A contains three designed siRNAs for AP3S2 gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Art. -Nr.: HY-RI01652A
hsa-miR-548ap-3p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs have 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 1 cholesterol group at the 3' end, and full-length nucleotide 2'-methoxy modification. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
Art. -Nr.: HY-RI01652
hsa-miR-548ap-3p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA inhibitors have full-length nucleotide 2'-methoxy modification. The miRNA inhibitors strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning.
Art. -Nr.: HY-R01652A
hsa-miR-548ap-3p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. They are designed to mimic endogenous miRNAs and recommended for miRNA functional studies. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo.
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
