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4-Cyano-3-methylisoquinoline

4-Cyano-3-methylisoquinoline is an inhibitor for protein kinase A (PKA) with an IC₅₀ of micromolar level. 4-Cyano-3-methylisoquinoline reverses morphine tolerance in mouse model.

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CAS No.: 161468-32-2
Formule: C₁₁H₈N₂
Masse moléculaire:168.19

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Data Sheet (269 KB)

4-Cyano-3-methylisoquinoline Chemical Structure

CAS No.: 161468-32-2

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Description

4-Cyano-3-methylisoquinoline is an inhibitor for protein kinase A (PKA) with an IC₅₀ of micromolar level. 4-Cyano-3-methylisoquinoline reverses morphine tolerance in mouse model^[1].

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Chemical Information

CAS No. 161468-32-2
Masse moléculaire 168.19
Formule C₁₁H₈N₂
SMILES

N#CC1=C(N=CC2=C1C=CC=C2)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Smith FL, et al., The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA. Brain Res. 2003 Sep 19;985(1):78-88. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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4-Cyano-3-methylisoquinoline

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4-Cyano-3-methylisoquinoline

Voir tous les produits spécifiques à Isoform PKA

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

4-Cyano-3-methylisoquinoline Related Classifications

Cat. No.: HY-112330