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Cergutuzumab

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Cergutuzumab is a fully human IgG1 antibody that targets carcinoembryonic antigen (CEA, CEACAM5, CD66e). Cergutuzumab can be used to form the recombinant protein Cergutuzumab amunaleukin (HY-P99498).

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  • Pureté: 98.86%
  • CAS No.: 1622305-37-6
  • Masse moléculaire:145.595 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Cergutuzumab
  • Experimental Validation Results for Cergutuzumab
  • Experimental Validation Results for Cergutuzumab
  • Cergutuzumab Chemical Structure
    Cergutuzumab Chemical Structure
CAS No.: 1622305-37-6
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Assay Types
  • 1/16

    IgG1-kappa

  • 1/16

    Immobilized CEACAM5 Protein, Human (HEK293, His, HY-P70675) can bind Cergutuzumab. The EC50 for this effect is 4.392 ng/mL.

  • 1/16

    Flow cytometric analysis of 1×106 MCF-7 cells with Cergutuzumab (HY-P991060, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.

  • Cergutuzumab Chemical Structure
    1/16
  • Cergutuzumab
  • Immobilized CEACAM5 Protein, Human (HEK293, His, HY-P70675) can bind Cergutuzumab. The EC50 for this effect is 4.392 ng/mL.
  • Flow cytometric analysis of 1×106 MCF-7 cells with Cergutuzumab (HY-P991060, red). Cells were fixed with 4% paraformaldehyde and permeabilised with 90% methanol. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1 kappa Isotype Control (HY-P99001, blue) was used as the isotype control.
  • IgG1-kappa