1622305-37-6
1622305-37-6
Chemical Structure
Cergutuzumab
- CAS No.: 1622305-37-6
- Formula:N/A
- Molecular Weight:(145.595 kDa)
SMILES: [Cergutuzumab]
Biological Activity: Cergutuzumab is a fully human IgG1 antibody that targets carcinoembryonic antigen (CEA, CEACAM5, CD66e). Cergutuzumab can be used to form the recombinant protein Cergutuzumab amunaleukin (HY-P99498)[1][2].
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Cergutuzumab | 98.86% | Cergutuzumab is a fully human IgG1 antibody that targets carcinoembryonic antigen (CEA, CEACAM5, CD66e). Cergutuzumab can be used to form the recombinant protein Cergutuzumab amunaleukin (HY-P99498). | ||||||||||||||||||||
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References
- [1]. Flisikowska T, et al. A humanized minipig model for the toxicological testing of therapeutic recombinant antibodies. Nat Biomed Eng. 2022;6(11):1248-1256. [Content Brief]
- [2]. Klein C, et al. Cergutuzumab amunaleukin (CEA-IL2v), a CEA-targeted IL-2 variant-based immunocytokine for combination cancer immunotherapy: Overcoming limitations of aldesleukin and conventional IL-2-based immunocytokines. Oncoimmunology. 2017;6(3):e1277306. Published 2017 Jan 11. [Content Brief]
