Adam9 - ADAM metallopeptidase domain 9 Gene

Also Known as MDC9

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 290834

Summary

Predicted to enable several functions, including SH3 domain binding activity; metalloendopeptidase activity involved in amyloid precursor protein catabolic process; and protein kinase C binding activity. Involved in response to antineoplastic agent and response to laminar fluid shear stress. Located in basolateral plasma membrane and cell surface. Biomarker of Alzheimer's disease and status epilepticus. Human ortholog(s) of this gene implicated in cone-rod dystrophy 9. Orthologous to human ADAM9 (ADAM metallopeptidase domain 9). [provided by Alliance of Genome Resources, Apr 2022]

Adam9 Products (1)

mRNA Protein Name
NM_001014772.2 NP_001014772.2 disintegrin and metalloproteinase domain-containing protein 9 precursor

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in response to antineoplastic agent IEP
IEP: Inferred from expression pattern
21503882 RGD
involved in response to laminar fluid shear stress IEP
IEP: Inferred from expression pattern
11156854 RGD
Cellular Component GO Annotation Evidence Références Source
located in basolateral plasma membrane IDA
IDA: Inferred from direct assay
10752518 RGD
located in cell surface IDA
IDA: Inferred from direct assay
10752518 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

disintegrin and metalloproteinase domain-containing protein 9

  • a disintegrin and metallopeptidase domain 9 (meltrin gamma)

  • a disintegrin and metalloproteinase domain 9 (meltrin gamma)

  • meltrin gamma

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive MoleculesInhibitory Antibodies (1)
Cat. No. Nom du produit Effect
Pureté Phase
HY-P990027 Izeltabart Inhibitor 98.62% Phase 2

Pre-clinical Phase

Bioactive Molecules (7)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-139441 DM21 Inhibitor 99.34% Unkown
HY-P3722A Mca-PLAQAV-Dpa-RSSSR-NH2 TFA 99.54% Unkown
HY-124813 PDZ1i Inhibitor 99.29% Unkown
HY-P3722 Mca-PLAQAV-Dpa-RSSSR-NH2 Substrate 99.33% Unkown
HY-RS00289 ADAM9 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17598 Adam9 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24058 Adam9 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Adam9 NCBI NCBI:8754
Mus musculus Adam9 NCBI NCBI:11502