Cers2 - ceramide synthase 2 Gene

Also Known as Lass2

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 310667

Summary

Predicted to enable sphingosine N-acyltransferase activity. Involved in negative regulation of Schwann cell migration; negative regulation of Schwann cell proliferation involved in axon regeneration; and negative regulation of axon regeneration. Predicted to be located in endoplasmic reticulum membrane and nucleus. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human CERS2 (ceramide synthase 2). [provided by Alliance of Genome Resources, Apr 2022]

Cers2 Products (1)

mRNA Protein Name
NM_001033700.2 NP_001028872.2 ceramide synthase 2

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Références Source
involved in negative regulation of Schwann cell migration IMP
IMP: Inferred from mutant phenotype
22393241 RGD
involved in negative regulation of Schwann cell proliferation IMP
IMP: Inferred from mutant phenotype
22393241 RGD
involved in negative regulation of Schwann cell proliferation involved in axon regeneration IMP
IMP: Inferred from mutant phenotype
22393241 RGD
involved in negative regulation of axon regeneration IMP
IMP: Inferred from mutant phenotype
22393241 RGD
involved in response to immobilization stress IEP
IEP: Inferred from expression pattern
34449011 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceramide synthase 2

  • LAG1 homolog, ceramide synthase 2

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (6)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-133490A ST1074 Inducer 99.41% Unkown
HY-133491 ST1060 Inhibitor / Unkown
HY-183140 DH20931 Activator / Unkown
HY-RS02537 CERS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22435 Cers2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28958 Cers2 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cers2 NCBI NCBI:29956