Fignl1 - fidgetin-like 1 Gene

Species: Mus musculus

Gene Type: protein coding
Gene ID: 60530

Summary

Predicted to enable microtubule-severing ATPase activity. Involved in several processes, including male meiotic nuclear division; osteoblast differentiation; and osteoblast proliferation. Acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway. Located in nucleus and perinuclear region of cytoplasm. Is expressed in brain ventricular layer and inferior colliculus. Orthologous to human FIGNL1 (fidgetin like 1). [provided by Alliance of Genome Resources, Apr 2022]

Fignl1 Products (3)

mRNA Protein Name
NM_001163359.1 NP_001156831.1 fidgetin-like protein 1
NM_001163360.1 NP_001156832.1 fidgetin-like protein 1
NM_021891.3 NP_068691.2 fidgetin-like protein 1

Gene Ontology

  • Biological Process
  • Cellular Component
Biological Process GO Annotation Evidence Références Source
involved in male meiotic nuclear division IMP
IMP: Inferred from mutant phenotype
22110678 MGI
involved in negative regulation of apoptotic process IMP
IMP: Inferred from mutant phenotype
20886204 MGI
acts upstream of or within negative regulation of intrinsic apoptotic signaling pathway IMP
IMP: Inferred from mutant phenotype
20886204 MGI
involved in osteoblast differentiation IMP
IMP: Inferred from mutant phenotype
17352653 MGI
involved in osteoblast proliferation IMP
IMP: Inferred from mutant phenotype
17352653 MGI
involved in regulation of cell cycle IMP
IMP: Inferred from mutant phenotype
20886204 MGI
Cellular Component GO Annotation Evidence Références Source
located in cytoplasm IDA
IDA: Inferred from direct assay
17352653 MGI
located in nucleus IDA
IDA: Inferred from direct assay
17352653 MGI
located in perinuclear region of cytoplasm IDA
IDA: Inferred from direct assay
22110678 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

fidgetin-like protein 1

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS04947 FIGNL1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Fignl1 NCBI NCBI:63979