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Art. -Nr.: HY-161642

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DENV-2/ZIKV-IN-1

DENV-2/ZIKV-IN-1 (Compd 16a) is a dual inhibitor of Dengue virus (DENV) and Zika virus (ZIKV) with EC₅₀s of 1.4 and 2.4 μM, respectively.

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Formel: C₁₉H₂₃ClF₃N₅
Molecular Weight:413.87

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

DENV-2/ZIKV-IN-1 Chemical Structure

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

DENV-2/ZIKV-IN-1 (Compd 16a) is a dual inhibitor of Dengue virus (DENV) and Zika virus (ZIKV) with EC₅₀s of 1.4 and 2.4 μM, respectively^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Vero	CC₅₀	23.83 μM Compound: 16a	Cytotoxicity against African green monkey Vero cells assessed as cell viability measured after 72 hrs by MTT assay Cytotoxicity against African green monkey Vero cells assessed as cell viability measured after 72 hrs by MTT assay	[PMID: 38718623]

Chemical Information

Molecular Weight 413.87
Formel C₁₉H₂₃ClF₃N₅
SMILES

ClC1=CC=C(CNC2=CC(C(F)(F)F)=NC(NCCN3CCCCC3)=N2)C=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Gallo FN, et al. Antiviral drug discovery: Pyrimidine entry inhibitors for Zika and dengue viruses. Eur J Med Chem. 2024 Jun 5;272:116465. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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