Ahcy - S-adenosylhomocysteine hydrolase Gene

Also Known as CuBP; SAHH

Species: Mus musculus

Gene Type: protein coding
Gene ID: 269378

Summary

Enables adenosylhomocysteinase activity; copper ion binding activity; and protein self-association. Acts upstream of or within S-adenosylhomocysteine catabolic process. Located in cytosol. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in hypermethioninemia with deficiency of S-adenosylhomocysteine hydrolase. Orthologous to human AHCY (adenosylhomocysteinase). [provided by Alliance of Genome Resources, Apr 2022]

Ahcy Products (1)

mRNA Protein Name
NM_016661.3 NP_057870.3 adenosylhomocysteinase

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Verweise Source
enables NAD binding IDA
IDA: Inferred from direct assay
7657650 MGI
enables adenosylhomocysteinase activity IDA
IDA: Inferred from direct assay
7657650 MGI
enables copper ion binding IDA
IDA: Inferred from direct assay
8419320 MGI
enables identical protein binding IPI
IPI: Inferred from physical interaction
8419320 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15102471 MGI
Biological Process GO Annotation Evidence Verweise Source
acts upstream of or within S-adenosylhomocysteine catabolic process IDA
IDA: Inferred from direct assay
12023972 MGI
Cellular Component GO Annotation Evidence Verweise Source
located in cytosol IDA
IDA: Inferred from direct assay
8419320 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

adenosylhomocysteinase

  • S-adenosyl-L-homocysteine hydrolase

  • adoHcyase

  • liver copper-binding protein

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (7)
Art. -Nr. Produktname
Wirkung
Reinheit
Rare Diseases
HY-10442 3-Deazaneplanocin A Inhibitor 99.97% Unkown
HY-12186 3-Deazaneplanocin A hydrochloride Inhibitor 99.98% Unkown
HY-112639 Aristeromycin Inhibitor 99.10% Unkown
HY-149048 Adenosylhomocysteinase / Unkown
HY-RS00476 AHCY Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16799 Ahcy Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23240 Ahcy Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ahcy NCBI NCBI:191