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Art. -Nr.: HY-186061

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HCN2-IN-4

HCN2-IN-4 is an orally active HCN2 ion channel inhibitor, with an IC₅₀ of 3 nM. HCN2-IN-4 inhibits the activity of HCN2 ion channels. HCN2-IN-4 can be used in the research of pain, tinnitus and central nervous system diseases.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 3080809-13-5
Formel: C₂₁H₁₈FN₅O₄S
Molecular Weight:455.46

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

HCN2-IN-4 Chemical Structure

CAS. Nr.: 3080809-13-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

In Vitro

HCN2-IN-4 (Compound 49) potently and selectively inhibits human HCN2 channels, with an IC₅₀ of 3 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 3080809-13-5
Molecular Weight 455.46
Formel C₂₁H₁₈FN₅O₄S
SMILES

O=C(C1=CC=NS1)NC2=NN(C[C@@H](C)OC)C3=NC=C(C4=CC=C(OCO5)C5=C4F)C=C23
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Ashok Arasappan, et al. Azaindazole derivatives useful as hcn2 modulators. WO2025072040. 2025-04-03.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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