HCN2 modulator-8
HCN2 modulator-8 is a pyrazolopyridine derivative and selective HCN2 inhibitor. HCN2 modulator-8 can be used for the research of pain, tinnitus, central nervous system disorders, psychiatric disorders, mood disorders.
For research use only. We do not sell to patients.
- CAS No.: 3080809-12-4
- Formula: C21H18FN5O4S
- Molecular Weight:455.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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KCNQ2 |
HCN2 modulator-8 (S-configuration 49) potently and selectively inhibited human HCN2 channels, with an HCN2 IC50 of 3 nM, HCN1 IC50 of 186 nM, and HCN4 IC50 of 87 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3080809-12-4
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Molecular Weight 455.46
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Formula C21H18FN5O4S
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SMILES
O=C(C1=CC=NS1)NC2=NN(C[C@H](C)OC)C3=NC=C(C4=CC=C(OCO5)C5=C4F)C=C23
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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