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LMP2A (426-434)

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LMP2A (426-434) is a HLA-A2-restricted cytotoxic T lymphocyte (CTL) epitope of Epstein-Barr virus (EBV) latent membrane protein 2A (LMP2A). LMP2A (426-434) can trigger an immune response in individuals expressing different HLA-A*02 subtypes (A*02:01, A*02:03, A*02:06 and A*02:07). LMP2A (426-434) can induce a strong IFN-γ secretion response, stimulating the production of a high proportion of CD8⁺ IFN-γ⁺ T cells. LMP2A (426-434) induces specific CTLs to effectively kill target cells expressing LMP2A. LMP2A (426-434) can be used to study EBV-related malignant tumors (such as Hodgkin's disease and nasopharyngeal carcinoma) .

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Reinheit: 96.09%
CAS. Nr.: 152274-91-4
Formel: C₃₉H₇₁N₉O₁₁S₂
Molecular Weight:906.16

Speicherung:

Sealed storage, away from moisture.

Powder -80°C, 2 years , -20°C, 1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

LMP2A (426-434) Chemical Structure

CAS. Nr.: 152274-91-4

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise
Help & FAQs
Bioz

Biologische Aktivität

Beschreibung

In Vitro

LMP2A (426-434) (20 μg/mL, 24 h) induces IFN-γ secreting cells at a frequency of 80.6 SFC/5×10⁴ CD8⁺ T cells^[1].
LMP2A (426-434) (20 μg/mL, 2 weeks) stimulation significantly increased the proportion of CD8⁺IFN-γ⁺ cells^[1].
LMP2A (426-434) (20 μg/mL, 4 h)-specific CTLs effectively kills peptide-pulsed T2 cells and 293T-LMP2A cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 152274-91-4
Appearance Solid
Molecular Weight 906.16
Formel C₃₉H₇₁N₉O₁₁S₂
Color White to off-white
Sequence

Cys-Leu-Gly-Gly-Leu-Leu-Thr-Met-Val
Sequence Shortening

CLGGLLTMV
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Sealed storage, away from moisture

Powder	-80°C	2 years
	-20°C	1 year

* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : ≥ 100 mg/mL (110.36 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

* "≥" means soluble, but saturation unknown.

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

1.1036 mL

5.5178 mL

11.0356 mL

5 mM

0.2207 mL

1.1036 mL

2.2071 mL

10 mM

0.1104 mL

0.5518 mL

1.1036 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Wang B, et al. Computational prediction and identification of Epstein-Barr virus latent membrane protein 2A antigen-specific CD8+ T-cell epitopes. Cell Mol Immunol. 2009 Apr;6(2):97-103. [Content Brief]

[2]. Lai J, et al. TCR-like antibodies mediate complement and antibody-dependent cellular cytotoxicity against Epstein-Barr virus-transformed B lymphoblastoid cells expressing different HLA-A*02 microvariants. Sci Rep. 2017 Aug 30;7(1):9923. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	1.1036 mL	5.5178 mL	11.0356 mL	27.5889 mL
	5 mM	0.2207 mL	1.1036 mL	2.2071 mL	5.5178 mL
	10 mM	0.1104 mL	0.5518 mL	1.1036 mL	2.7589 mL
	15 mM	0.0736 mL	0.3679 mL	0.7357 mL	1.8393 mL
	20 mM	0.0552 mL	0.2759 mL	0.5518 mL	1.3794 mL
	25 mM	0.0441 mL	0.2207 mL	0.4414 mL	1.1036 mL
	30 mM	0.0368 mL	0.1839 mL	0.3679 mL	0.9196 mL
	40 mM	0.0276 mL	0.1379 mL	0.2759 mL	0.6897 mL
	50 mM	0.0221 mL	0.1104 mL	0.2207 mL	0.5518 mL
	60 mM	0.0184 mL	0.0920 mL	0.1839 mL	0.4598 mL
	80 mM	0.0138 mL	0.0690 mL	0.1379 mL	0.3449 mL
	100 mM	0.0110 mL	0.0552 mL	0.1104 mL	0.2759 mL

Keywords

100 mg

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Lösungsmittel & Löslichkeit
- In Vitro
Reinheit & Dokumentation
Verweise

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LMP2A (426-434)

Anti-Infection Compound Library

Immunology/Inflammation Compound Library

Pyroptosis Compound Library

Peptide Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Autoimmune Disease Compound Library

Highly Selective Activators Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Peptide Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

LMP2A (426-434)

Anti-Infection Compound Library

Immunology/Inflammation Compound Library

Pyroptosis Compound Library

Peptide Library

Membrane Protein-targeted Compound Library

Membrane Receptor-targeted Compound Library

Autoimmune Disease Compound Library

Highly Selective Activators Library

Multi-Target Compound Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Peptide Compound Library

Bioactive Compound Library

High-Throughput Bioactive Compound Library

Biologische Aktivität

Chemical Information

Lösungsmittel & Löslichkeit

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

LMP2A (426-434) Related Classifications

Art. -Nr.: HY-P5470