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Art. -Nr.: HY-160252

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PHGDH-IN-4

PHGDH-IN-4 is a potent 3-phosphoglycerate dehydrogenase (PHGDH) inhibitor . PHGDH-IN-4 can be used for the research of cancer .

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2132969-16-3
Formel: C₂₁H₁₉Cl₂N₃O₅S
Molecular Weight:496.36

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

PHGDH-IN-4 Chemical Structure

CAS. Nr.: 2132969-16-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

PHGDH-IN-4 is a potent 3-phosphoglycerate dehydrogenase (PHGDH) inhibitor . PHGDH-IN-4 can be used for the research of cancer ^[1].

In Vitro

PHGDH-IN-4 (example I-93) inhibits PHGDH activity with an IC₅₀ of 0.001-1 μΜ^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 2132969-16-3
Molecular Weight 496.36
Formel C₂₁H₁₉Cl₂N₃O₅S
SMILES

O=C(C1=CC2=C(N1C)C=CC(Cl)=C2Cl)NC3(COC3)C4=CC=C(S(=O)(NC(C)=O)=O)C=C4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Nello Mainolfi. 3-phosphoglycerate dehydrogenase inhibitors and uses thereof. WO2017156165A1.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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