TCO-PEG3-amine
Based on 1 publication(s) in Google Scholar
TCO-PEG3-amine is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 96.49%
- CAS. Nr.: 1800507-93-0
- Formel: C17H32N2O5
- Molecular Weight:344.45
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Speicherung:Pure form -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) TCO-PEG3-amine
MoreAlle PROTAC Linkers Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1800507-93-0
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Appearance Liquid
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Molecular Weight 344.45
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Formel C17H32N2O5
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Color Light yellow to yellow
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SMILES
O=C(OC1CC/C=C\CCC1)NCCOCCOCCOCCN
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Pure form -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Cell Rep Methods
Efficiency landscape of bioorthogonal click reactions producing bispecific antibody conjugates. [Abstract]2026 Jun 15;6(6):101416. PMID: 42019503
Lösungsmittel & Löslichkeit
H2O : ≥ 100 mg/mL (290.32 mM)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 2.9032 mL | 14.5159 mL | 29.0318 mL | 72.5795 mL |
| 5 mM | 0.5806 mL | 2.9032 mL | 5.8064 mL | 14.5159 mL | |
| 10 mM | 0.2903 mL | 1.4516 mL | 2.9032 mL | 7.2579 mL | |
| 15 mM | 0.1935 mL | 0.9677 mL | 1.9355 mL | 4.8386 mL | |
| 20 mM | 0.1452 mL | 0.7258 mL | 1.4516 mL | 3.6290 mL | |
| 25 mM | 0.1161 mL | 0.5806 mL | 1.1613 mL | 2.9032 mL | |
| 30 mM | 0.0968 mL | 0.4839 mL | 0.9677 mL | 2.4193 mL | |
| 40 mM | 0.0726 mL | 0.3629 mL | 0.7258 mL | 1.8145 mL | |
| 50 mM | 0.0581 mL | 0.2903 mL | 0.5806 mL | 1.4516 mL | |
| 60 mM | 0.0484 mL | 0.2419 mL | 0.4839 mL | 1.2097 mL | |
| 80 mM | 0.0363 mL | 0.1814 mL | 0.3629 mL | 0.9072 mL | |
| 100 mM | 0.0290 mL | 0.1452 mL | 0.2903 mL | 0.7258 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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