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Cat. No.: HY-172675

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DEL-I25

1 Cited Publications

Customer Review

Based on 1 publication(s) in Google Scholar

DEL-I25 is a potent GPX4 activator. DEL-I25 protects cells from ferroptosis.

For research use only. We do not sell to patients.

CAS No.: 3036889-54-7
Formula: C₂₁H₂₃N₅O₃
Molecular Weight:393.44

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

DEL-I25 Chemical Structure

CAS No.: 3036889-54-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

DEL-I25 is a potent GPX4 activator. DEL-I25 protects cells from ferroptosis^[1].

IC₅₀ & Target

GPX4

All Glutathione Peroxidase Isoforms :

GPX1
GPX4

Chemical Information

CAS No. 3036889-54-7
Molecular Weight 393.44
Formula C₂₁H₂₃N₅O₃
SMILES

O=C(N1CC(NC(CCC2=CC=C(N)C=N2)=O)C1)CN3C(C4=CC=CC=C4C3)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Journal Impact Factor

Antioxidants (Basel)

Hesperidin from Chenpi Ameliorates Skin Photoaging by Targeting HSPA1L to Stabilize GPX4 and Suppress Ferroptosis. [Abstract]

2026 Apr 14;15(4):484. PMID: 42072126

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Liu H, et al. Selective Small-Molecule Activator of Patient-Derived GPX4 Variant. ACS Chem Biol. 2025 May 16;20(5):1107-1122. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Publications (1)
Purity & Documentation
References

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DEL-I25

Publications Citing Use of MedChemExpress (MCE) DEL-I25

All Glutathione Peroxidase Isoforms