RALYL - RALY RNA binding protein like Gene

Also Known as HNRPCL3

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 138046

About RALYL

Cytogenetic location: 8q21.2 Genomic coordinates (GRCh38): 8:84,182,787-84,921,844 (from NCBI)

This gene has 11 transcripts (splice variants), 256 orthologues and 6 paralogues. Biased expression in brain (RPKM 3.1), adrenal (RPKM 2.1) and 3 other tissues.

Summary

Enables identical protein binding activity. Located in nucleoplasm. [provided by Alliance of Genome Resources, Apr 2022]

RALYL Products (51)

mRNA Protein Name
NM_001100391.3 NP_001093861.1 RNA-binding Raly-like protein isoform 1
NM_001100392.3 NP_001093862.1 RNA-binding Raly-like protein isoform 2
NM_001100393.3 NP_001093863.1 RNA-binding Raly-like protein isoform 2
NM_001287243.3 NP_001274172.1 RNA-binding Raly-like protein isoform 3
NM_001287244.2 NP_001274173.1 RNA-binding Raly-like protein isoform 4
NM_001354305.2 NP_001341234.1 RNA-binding Raly-like protein isoform 2
NM_001354306.2 NP_001341235.1 RNA-binding Raly-like protein isoform 2
NM_001354307.2 NP_001341236.1 RNA-binding Raly-like protein isoform 3
NM_001354308.2 NP_001341237.1 RNA-binding Raly-like protein isoform 2
NM_001354309.2 NP_001341238.1 RNA-binding Raly-like protein isoform 3
NM_001354310.2 NP_001341239.1 RNA-binding Raly-like protein isoform 5
NM_001354311.2 NP_001341240.1 RNA-binding Raly-like protein isoform 6
NM_001354312.2 NP_001341241.1 RNA-binding Raly-like protein isoform 3
NM_001354313.2 NP_001341242.1 RNA-binding Raly-like protein isoform 6
NM_001354314.2 NP_001341243.1 RNA-binding Raly-like protein isoform 7
NM_001354315.2 NP_001341244.1 RNA-binding Raly-like protein isoform 3
NM_001354316.2 NP_001341245.1 RNA-binding Raly-like protein isoform 2
NM_001354317.2 NP_001341246.1 RNA-binding Raly-like protein isoform 3
NM_001354318.2 NP_001341247.1 RNA-binding Raly-like protein isoform 3
NM_001354319.2 NP_001341248.1 RNA-binding Raly-like protein isoform 6
NM_001354320.2 NP_001341249.1 RNA-binding Raly-like protein isoform 2
NM_001354321.2 NP_001341250.1 RNA-binding Raly-like protein isoform 8
NM_001354322.2 NP_001341251.1 RNA-binding Raly-like protein isoform 9
NM_001354323.2 NP_001341252.1 RNA-binding Raly-like protein isoform 10
NM_001354325.2 NP_001341254.1 RNA-binding Raly-like protein isoform 2
NM_001413300.1 NP_001400229.1 RNA-binding Raly-like protein isoform 3
NM_001413301.1 NP_001400230.1 RNA-binding Raly-like protein isoform 11
NM_001413302.1 NP_001400231.1 RNA-binding Raly-like protein isoform 3
NM_001413303.1 NP_001400232.1 RNA-binding Raly-like protein isoform 12
NM_001413304.1 NP_001400233.1 RNA-binding Raly-like protein isoform 2
NM_001413305.1 NP_001400234.1 RNA-binding Raly-like protein isoform 2
NM_001413306.1 NP_001400235.1 RNA-binding Raly-like protein isoform 13
NM_001413307.1 NP_001400236.1 RNA-binding Raly-like protein isoform 3
NM_001413308.1 NP_001400237.1 RNA-binding Raly-like protein isoform 2
NM_001413309.1 NP_001400238.1 RNA-binding Raly-like protein isoform 14
NM_001413310.1 NP_001400239.1 RNA-binding Raly-like protein isoform 15
NM_001413311.1 NP_001400240.1 RNA-binding Raly-like protein isoform 2
NM_001413312.1 NP_001400241.1 RNA-binding Raly-like protein isoform 12
NM_001413313.1 NP_001400242.1 RNA-binding Raly-like protein isoform 15
NM_001413314.1 NP_001400243.1 RNA-binding Raly-like protein isoform 2
NM_001413315.1 NP_001400244.1 RNA-binding Raly-like protein isoform 3
NM_001413316.1 NP_001400245.1 RNA-binding Raly-like protein isoform 2
NM_001413318.1 NP_001400247.1 RNA-binding Raly-like protein isoform 2
NM_001413319.1 NP_001400248.1 RNA-binding Raly-like protein isoform 14
NM_001413320.1 NP_001400249.1 RNA-binding Raly-like protein isoform 16
NM_001413321.1 NP_001400250.1 RNA-binding Raly-like protein isoform 2
NM_001413322.1 NP_001400251.1 RNA-binding Raly-like protein isoform 3
NM_001413323.1 NP_001400252.1 RNA-binding Raly-like protein isoform 17
NM_001413324.1 NP_001400253.1 RNA-binding Raly-like protein isoform 18
NM_001413329.1 NP_001400258.1 RNA-binding Raly-like protein isoform 19
NM_173848.7 NP_776247.3 RNA-binding Raly-like protein isoform 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence Références Source
enables identical protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
16189514 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

RALYL Protein Structure

RRM_1

RRM_1: RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) (23 - 85)

  • 0
  • 100
  • 200
  • 291 a.a.
Protein Preferred Names Protein Names

RNA-binding Raly-like protein

  • heterogeneous nuclear ribonucleoprotein C-like 3

RALYL Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
RALYL Q86SE5 HNRNPC Homo sapiens P07910
Y2H Array
25416956
Intra
RALYL Q86SE5 HNRNPC Homo sapiens P07910
Y2H Prey Pooling
25416956
Intra
RALYL Q86SE5 BYSL Homo sapiens Q13895
Y2H Array
25416956
Intra
RALYL Q86SE5 RBM41 Homo sapiens Q96IZ5
Y2H Array
25416956
Intra
RALYL Q86SE5 THAP1 Homo sapiens Q9NVV9
Y2H Prey Pooling
25416956
Intra
RALYL Q86SE5 THAP1 Homo sapiens Q9NVV9
Y2H Array
25416956
Intra
RALYL Q86SE5 RALYL Homo sapiens Q86SE5
Y2H Pooling
16189514
Intra
RALYL Q86SE5 RALYL Homo sapiens Q86SE5
Y2H Pooling
19447967
Intra
RALYL Q86SE5 AEN Homo sapiens Q8WTP8
Validated Y2H
25416956
Intra
RALYL Q86SE5 AEN Homo sapiens Q8WTP8
Y2H Prey Pooling
25416956
Intra
RALYL Q86SE5 RALYL Homo sapiens Q86SE5
Y2H Array
25416956
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Diseases

Diseases Alias
Bardet-Biedl Syndrome 1

  • BBS1

  • Bardet-Biedl Syndrome 1, Modifier Of

  • Bardet-Biedl Syndrome

  • BBS

  • Bardet-Biedl Syndrome, Type 1

  • Laurence-Moon-Bardet-Biedl Syndrome
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (2)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS11636 RALYL Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22766 Ralyl Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Macaca mulatta RALYL VGNC VGNC:82217
Bos taurus RALYL VGNC VGNC:55755
Mus musculus RALYL MGD MGI:1924147
Rattus norvegicus RALYL RGD RGD:1305844
Others RALYL NCBI