CLEC2D - C-type lectin domain family 2 member D Gene

Also Known as CLAX; LLT1; OCIL

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 29121

About CLEC2D

Cytogenetic location: 12p13.31 Genomic coordinates (GRCh38): 12:9,669,713-9,699,553 (from NCBI)

This gene has 16 transcripts (splice variants), 351 orthologues and 23 paralogues. Broad expression in lymph node (RPKM 24.3), appendix (RPKM 12.2) and 24 other tissues.

Summary

This gene encodes a member of the natural killer cell receptor C-type lectin family. The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain. Several alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Oct 2010]

CLEC2D Products (5)

mRNA Protein Name
NM_001004419.5 NP_001004419.1 C-type lectin domain family 2 member D isoform 2
NM_001197317.3 NP_001184246.1 C-type lectin domain family 2 member D isoform 3
NM_001197318.3 NP_001184247.1 C-type lectin domain family 2 member D isoform 4
NM_001197319.3 NP_001184248.1 C-type lectin domain family 2 member D isoform 5
NM_013269.6 NP_037401.1 C-type lectin domain family 2 member D isoform 1

Gene Ontology

  • Molecular Function
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
21572041 GOA
Cellular Component GO Annotation Evidence Références Source
located in cell surface IDA
IDA: Inferred from direct assay
20843815 GOA
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
20843815 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

CLEC2D Protein Structure

Lectin_C

Lectin_C: Lectin C-type domain (93 - 186)

  • 0
  • 100
  • 191 a.a.
Protein Preferred Names Protein Names

C-type lectin domain family 2 member D

  • C-type lectin related f

Recombinant CLEC2D Proteins

Cat. No. Nom du produit Accession Pureté
HY-P77901 OCIL/CLEC2D Protein, Human (HEK293, Fc-Avi) Q9UHP7-1 (R60-V191) ≥ 95%, as determined by Bis-Tris PAGE.
HY-P77902 OCIL/CLEC2D Protein, Human (Biotinylated, HEK293, Fc-Avi) Q9UHP7-1 (R60-V191) ≥ 95%, as determined by Bis-Tris PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-N0028 Forsythiaside A 99.79% Unkown
HY-P11003 PTD-N5-1 Inhibitor / Unkown
HY-RS02788 CLEC2D Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17617 Clec2d Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS24077 Clec2d Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus CLEC2D RGD RGD:620070
Canis familiaris CLEC2D VGNC VGNC:39330
Macaca mulatta CLEC2D VGNC VGNC:71177
Felis catus CLEC2D VGNC VGNC:60947
Others CLEC2D NCBI