Sap30 - sin3 associated polypeptide Gene

Also Known as 30kDa

Species: Mus musculus

Gene Type: protein coding
Gene ID: 60406

Summary

Predicted to enable transcription corepressor activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II and skeletal muscle cell differentiation. Located in nucleus. Is expressed in several structures, including branchial arch; early embryo; embryo mesenchyme; forelimb bud; and sensory organ. Orthologous to human SAP30 (Sin3A associated protein 30). [provided by Alliance of Genome Resources, Apr 2022]

Sap30 Products (1)

mRNA Protein Name
NM_021788.3 NP_068560.1 histone deacetylase complex subunit SAP30

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence Références Source
enables protein binding IPI
IPI: Inferred from physical interaction
9702189 MGI
Biological Process GO Annotation Evidence Références Source
acts upstream of or within negative regulation of transcription by RNA polymerase II IDA
IDA: Inferred from direct assay
9702189 MGI
acts upstream of or within skeletal muscle cell differentiation IMP
IMP: Inferred from mutant phenotype
22147266 MGI
Cellular Component GO Annotation Evidence Références Source
located in nucleus IDA
IDA: Inferred from direct assay
11101889 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

histone deacetylase complex subunit SAP30

  • 30 kDa Sin3-associated polypeptide

  • Sin3-associated protein

  • sin3 associated polypeptide, 30kD

  • sin3 corepressor complex subunit SAP30

  • sin3-associated polypeptide p30

  • sin3-associated polypeptide, 30 kDa

Sap30 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
Sap30 O88574 Ncor1 Mus musculus Q60974
Pull Down
9702189
Intra
Sap30 O88574 Sin3a Mus musculus Q60520
Pull Down
9702189
Intra
Sap30 O88574 Sin3a Mus musculus Q60520
CoIP
9702189
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (4)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS12440 SAP30 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12441 SAP30BP Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21751 Sap30 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28269 Sap30 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sap30 NCBI NCBI:8819