Ptger3 - prostaglandin E receptor 3 (subtype EP3) Gene

Also Known as EP3; Pgerep3; Ptgerep3

Species: Mus musculus

Gene Type: protein coding
Gene ID: 19218

Summary

Enables prostaglandin E receptor activity. Involved in positive regulation of fever generation. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; bicarbonate transport; and fever generation. Located in plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human PTGER3 (prostaglandin E receptor 3). [provided by Alliance of Genome Resources, Apr 2022]

Ptger3 Products (2)

mRNA Protein Name
NM_001359745.2 NP_001346674.1 prostaglandin E2 receptor EP3 subtype isoform 1
NM_011196.4 NP_035326.2 prostaglandin E2 receptor EP3 subtype isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables prostaglandin E receptor activity IDA
IDA: Inferred from direct assay
7945376 MGI
enables prostaglandin E receptor activity IMP
IMP: Inferred from mutant phenotype
7733888 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
8076637 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within adenylate cyclase-modulating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
8223569 MGI
acts upstream of or within bicarbonate transport IMP
IMP: Inferred from mutant phenotype
10535876 MGI
acts upstream of or within fever generation IDA
IDA: Inferred from direct assay
9751056 MGI
acts upstream of or within fever generation IMP
IMP: Inferred from mutant phenotype
9751056 MGI
acts upstream of or within phospholipase C-activating G protein-coupled receptor signaling pathway IDA
IDA: Inferred from direct assay
7945376 MGI
acts upstream of or within positive regulation of cytosolic calcium ion concentration IDA
IDA: Inferred from direct assay
7945376 MGI
involved in positive regulation of fever generation IMP
IMP: Inferred from mutant phenotype
19940926 MGI
acts upstream of or within positive regulation of urine volume IMP
IMP: Inferred from mutant phenotype
9843913 MGI
acts upstream of or within response to lipopolysaccharide IMP
IMP: Inferred from mutant phenotype
15834430 MGI
Cellular Component GO Annotation Evidence References Source
located in plasma membrane IDA
IDA: Inferred from direct assay
8223569 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

prostaglandin E2 receptor EP3 subtype

  • PGE receptor EP3 subtype

  • PGE2 receptor EP3 subtype

  • prostaglandin E receptor EP3 subtype

  • prostanoid EP3 receptor

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS11377 PTGER3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20586 Ptger3 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27094 Ptger3 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Ptger3 NCBI NCBI:5733