Estrogen Receptor/ERR Control
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(S)-ErSO
0 Images(S)-ErSO is the dextrorotatory enantiomer of ErSO. (S)-ErSO is inactive in MCF-7 cells (from patent WO2020009958A1, compound (s)-105).
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(±)-ErSO
0 ImagesCat. No.: HY-132247ACAS No.: 2407860-40-4(±)-ErSO is the racemate of ErSO. ErSO is a selective anticipatory unfolded protein response (a-UPR) activator.
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(R)-OP-1074
0 Images(R)-OP-1074 is an isomer of OP-1074 (HY-125263) and can serve as a control compound in experiments. OP-1074, a pure anti-estrogen drug, is a selective ER degrader (PA-SERD) with specific anti-estrogenic activity against ERα and ERβ, inhibiting 17β-estradiol (E2)-stimulated transcription with IC50 values of 1.6 and 3.2 nM, respectively.
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Anticancer agent 341
0 ImagesCat. No.: HY-184900CAS No.: 3099598-43-0Anticancer agent 341 (Compound III-163) is a non-ERα-dependent cytotoxic agent with its GI50 for MCF cells is 0.05-0.5 μΜ. Anticancer agent 341 exhibits GI50 for T-Rex 293 cells regardless of whether Doxycycline (Dox) (HY-N0565) is added of all < 0.05 μΜ. Anticancer agent 341 can be used in breast cancer research.
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Raloxifene dimethyl ester hydrochloride
0 ImagesCat. No.: HY-135596CAS No.: 84449-82-1Synonyms: Diacyl-raloxifene hydrochloride; Raloxifene diacyl analogRaloxifene dimethyl ester hydrochloride is an analog of Raloxifene, extracted from patent US5464845A, compound 28.
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10-Chloroestra-1,4-diene-3,17-dione
0 ImagesCat. No.: HY-N13290CAS No.: 91413-55-7Synonyms: 10-CIEsra10-Chloroestra-1,4-diene-3,17-dione (10-CIEsra) is a derivative of estrogen receptor.
