3099598-43-0
Chemical Structure
Anticancer agent 341
- CAS. Nr.: 3099598-43-0
- Formula:C54H57N7O3S
- Molecular Weight:884.14
InChIKey: OKVLLWRHVCUCOH-JGLNEIJQSA-N
SMILES: CC1=C(C)SC2=C1C(C3=CC=C(N4CCC(CC4)CC5(CCN(C6=CC=C([C@@H]7C8=CC=C(O)C=C8CC[C@@H]7C9=CC=CC=C9)C=C6)CC5)O)C=C3)=N[C@H](CC%10=NC=CO%10)C%11=NN=C(C)N2%11
Biological Activity: Anticancer agent 341 (Compound III-163) is a non-ERα-dependent cytotoxic agent with its GI50 for MCF cells is 0.05-0.5 μΜ. Anticancer agent 341 exhibits GI50 for T-Rex 293 cells regardless of whether Doxycycline (Dox) (HY-N0565) is added of all < 0.05 μΜ. Anticancer agent 341 can be used in breast cancer research[1].
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Anticancer agent 341 | Anticancer agent 341 (Compound III-163) is a non-ERα-dependent cytotoxic agent with its GI50 for MCF cells is 0.05-0.5 μΜ. Anticancer agent 341 exhibits GI50 for T-Rex 293 cells regardless of whether Doxycycline (Dox) (HY-N0565) is added of all < 0.05 μΜ. Anticancer agent 341 can be used in breast cancer research. | |||||||||||||||||||||
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Keywords
