179118-06-0
Chemical Structure
BSF2
- CAS No.: 179118-06-0
- Formula:C20H20N4O
- Molecular Weight:332.40
InChIKey: KUBQARQJQHKFTA-UHFFFAOYSA-N
SMILES: CC1=C(OC(C2=CC=C(C=C2)C(N)=N)=C1C)C3=CC=C(C=C3)C(N)=N
Biological Activity: BSF2 is a anti-Leishmania agent. BSF2 modulates gene expression linked to ubiquitination, chromatin remodeling, and peroxisomal membrane transport pathways in Leishmania braziliensis. BSF2 downregulates TNF, IL-17, NF-κB, and Toll-like receptor pathways in Leishmania-infected macrophages. BSF2 exerts leishmanicidal activity against intracellular Leishmania braziliensis amastigotes. BSF2 can be used for the research of american tegumentary leishmaniasis[1].
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BSF2 | BSF2 is a anti-Leishmania agent. BSF2 modulates gene expression linked to ubiquitination, chromatin remodeling, and peroxisomal membrane transport pathways in Leishmania braziliensis. BSF2 downregulates TNF, IL-17, NF-κB, and Toll-like receptor pathways in Leishmania-infected macrophages. BSF2 exerts leishmanicidal activity against intracellular Leishmania braziliensis amastigotes. BSF2 can be used for the research of american tegumentary leishmaniasis. | |||||||||||||||||||||
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Keywords
