MWAC-3429
MWAC-3429 is a potent SARS-CoV-2 Nsp13 helicase inhibitor. MWAC-3429 inhibits SARS-CoV-2 and SARS-CoV1 with EC50s of 5.39 (nLuc assay) and 17.00 μM (CPE assay), respectively, while showing low cytotoxicity in A549-hACE2 cells (CC50 > 50 μM). MWAC-3429 can be used for SARS-CoV-infection research.
For research use only. We do not sell to patients.
- CAS No.: 2093677-54-2
- Formula: C22H23N3O2S
- Molecular Weight:393.50
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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SARS-CoV-2 5.39 μM (EC50) |
SARS-CoV1 17.00 μM (EC50) |
Chemical Information
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CAS No. 2093677-54-2
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Molecular Weight 393.50
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Formula C22H23N3O2S
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SMILES
COC1=CC2=C(CC(N(C2)C(C3=CSC(CCN)=N3)=O)C4=CC=CC=C4)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)