Th2 cell-derived exosomes alleviate central nervous system inflammation and demyelination in experimental autoimmune encephalomyelitis by regulating inflammasomes to inhibit microglia activation

  • Mol Biol Rep. 2025 Nov 15;53(1):92. doi: 10.1007/s11033-025-11265-w.
Xianmin Cao  1 ,  Yufen Peng  2 ,  Shimin Liu  3 ,  Chao Zhou  3 ,  Liang Gao  2 ,  Jiajun Xiong  2 ,  Meihong Zhou  2 ,  Mengqi Xia  1 ,  Yingqiong Xiong  4
Affiliations
  • 1. Graduate School, Jiangxi Medical College of Nanchang University, No.461, Bayi Avenue, Nanchang City, Jiangxi Province, China.
  • 2. Department of Neurology, The First Affiliated Hospital of Nanchang University, No.17 Yongwai Zheng Street, Nanchang City, Jiangxi Province, China.
  • 3. Department of Neurology, Jiangxi Provincial People's Hospital, No. 152, Aiguo Road, Nanchang City, Jiangxi Province, China.
  • 4. Department of Neurology, The First Affiliated Hospital of Nanchang University, No.17 Yongwai Zheng Street, Nanchang City, Jiangxi Province, China. [email protected].
PMID: 41240231 DOI: 10.1007/s11033-025-11265-w
Keywords
Exosomes; Experimental autoimmune encephalom-yelitis; Inflammasome; Microglia; Multiple sclerosis; Th2 cell-derived exosomes.
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