MWAC-3429
MWAC-3429 is a potent SARS-CoV-2 Nsp13 helicase inhibitor. MWAC-3429 inhibits SARS-CoV-2 and SARS-CoV1 with EC50s of 5.39 (nLuc assay) and 17.00 μM (CPE assay), respectively, while showing low cytotoxicity in A549-hACE2 cells (CC50 > 50 μM). MWAC-3429 can be used for SARS-CoV-infection research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 2093677-54-2
- Fòrmula: C22H23N3O2S
- Peso molecular:393.50
-
Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
|
SARS-CoV-2 5.39 μM (EC50) |
SARS-CoV1 17.00 μM (EC50) |
Chemical Information
-
No. CAS 2093677-54-2
-
Peso molecular 393.50
-
Fòrmula C22H23N3O2S
-
SMILES
COC1=CC2=C(CC(N(C2)C(C3=CSC(CCN)=N3)=O)C4=CC=CC=C4)C=C1
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)