12-Hydroxyfusicoccin
12-Hydroxyfusicoccin (12-hFC) is a Fusicoccin (HY-122815) derivative. 12-Hydroxyfusicoccin lacks antiproliferative activity and is inactive to protein-protein interactionin and protein synthesis in cancer cells.
For research use only. We do not sell to patients.
- CAS No.: 2281679-00-1
- Formula: C30H49NO8
- Molecular Weight:551.71
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
12-hydroxyfusicoccin does not stabilize the 14-3-3ζ-GIGYF2 protein-protein interaction in HEK293 cells[1].
12-hydroxyfusicoccin (1 h) does not suppress global nascent protein synthesis in HEK293 cells[1].
12-hydroxyfusicoccin does not increase the binding of TTP to GIGYF2 in HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2281679-00-1
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Molecular Weight 551.71
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Formula C30H49NO8
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SMILES
C[C@]12C([C@H]([C@@H]([C@@H]([C@@]3([H])/C([C@H](CC3)COC)=C\1)C)O)O[C@@H]4[C@@H]([C@]5([H])[C@](CO[C@H]5OCCCN)([H])O4)O)=C(C[C@@H]2O)C(C)C
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Synonyms
12-hFC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)