Bacillibactin
Based on 1 Customer Validation
Bacillibactin (Corynebactin) is a cyclic tricatecholate siderophore. Bacillibactin’s primary function is to facilitate bacterial iron acquisition by chelating iron ions (Fe3+) from the environment, thereby aiding bacterial survival under iron-limited conditions. Bacillibactin exhibits direct antimicrobial activity, such as inhibition of the growth of the producing bacteria Pseudomonas aeruginosa and Aeromonas veronae, as well as plant pathogens such as Pseudomonas syringae.Bacillibactin can be used in antibacterial and antifungal research.
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.1%
- No. CAS: 95536-41-7
- Fòrmula: C39H42N6O18
- Peso molecular:882.78
-
Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Actividad biológica
-
Chemical Information
- Pureza y Documentación
- Referencias
-
Help & FAQs
Actividad biológica
Bacillibactin demonstrates strong inhibitory activity against Pseudomonas aeruginosa and Aeromonas veronii[1].
Bacillibactin significantly inhibites the growth of P. syringae pv. tomato, Pst under iron starvation conditions and inhibits the growth of a wider range of fungal pathogens (Such as Fusarium, Rhizoctonia, Aspergillus, Verticillium, etc.)[3].
Bacillibactin (10 μM) shows an inhibition rate of less than 20% against two human cancer cell lines (HepG2 liver cancer cells and MCF7 breast cancer cells), indicating that it does not exhibit significant in vitro anti-tumor activity[4].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
No. CAS 95536-41-7
-
Appearance Solid
-
Peso molecular 882.78
-
Fòrmula C39H42N6O18
-
SMILES
O=C(C1=C(C(O)=CC=C1)O)NCC(N[C@H]2[C@H](OC([C@H]([C@H](OC([C@H]([C@H](OC2=O)C)NC(CNC(C3=C(C(O)=CC=C3)O)=O)=O)=O)C)NC(CNC(C4=C(C(O)=CC=C4)O)=O)=O)=O)C)=O
-
Synonyms
Corynebactin
-
Structure Classification
-
Initial Source
Brevibacterium sp.
-
Envío
Room temperature in continental US; may vary elsewhere.
-
Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
-
Ficha de datos (271 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Instrucciones de manejo (2659 KB)
Referencias
[1]. Prazdnova E, et al. Bacillibactin, a Potential Bacillus-Based Antibacterial Non-Ribosomal Peptide: In Silico Studies for Targeting Common Fish Pathogens. Int J Mol Sci. 2025 Jun 17;26(12):5811. [Content Brief]
[2]. Pi H, Helmann JD. Genome-Wide Characterization of the Fur Regulatory Network Reveals a Link between Catechol Degradation and Bacillibactin Metabolism in Bacillus subtilis. mBio. 2018 Oct 30;9(5):e01451-18. [Content Brief]
[3]. Dimopoulou A, et al. Direct Antibiotic Activity of Bacillibactin Broadens the Biocontrol Range of Bacillus amyloliquefaciens MBI600. mSphere. 2021 Aug 25;6(4):e0037621. [Content Brief]
[4]. Zhou M, et al. Bacillibactin and Bacillomycin Analogues with Cytotoxicities against Human Cancer Cell Lines from Marine Bacillus sp. PKU-MA00093 and PKU-MA00092. Mar Drugs. 2018 Jan 10;16(1):22. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Bacillibactin Related Classifications
HY-160238 Related Classifications
Powered by Bioz