CK2-IN-11
CK2-IN-11 (32) is an allosteric CK2 inhibitor, with high selectivity for CK2 with IC50 values of 19.3 nM and 15.6 nM for the CK2α2β2 and the CK2α′2β2 isoforms, respectively.
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- No. CAS: 2938991-22-9
- Fòrmula: C23H22Br4Cl2N4O2
- Peso molecular:776.97
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
15.94 μM
Compound: 2; KN2
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Cytotoxicity against HEK293 cells assessed as reduction in cell viability incubated for 24 hrs by resazurin-based cytotoxicity assay
Cytotoxicity against HEK293 cells assessed as reduction in cell viability incubated for 24 hrs by resazurin-based cytotoxicity assay
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[PMID: 34323071] |
| HeLa | EC50 |
6.19 μM
Compound: 2; KN2
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Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by resazurin-based cytotoxicity assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability incubated for 24 hrs by resazurin-based cytotoxicity assay
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[PMID: 34323071] |
Chemical Information
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No. CAS 2938991-22-9
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Peso molecular 776.97
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Fòrmula C23H22Br4Cl2N4O2
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SMILES
O=C(NCCCCN1C=NC2=C(C(Br)=C(C(Br)=C21)Br)Br)CCC(NCCC3=CC=C(C(Cl)=C3)Cl)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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