iso-WAY-260022
iso-WAY-260022 (Compound 13R) is an orally active, brain-penetrant and selective norepinephrine transporter (hNET) inhibitor with an IC50 value of 140 nM. iso-WAY-260022 also shows inhibitory effects on human serotonin (hSERT) and dopamine transporters (hDAT). iso-WAY-260022 inhibits norepinephrine reuptake and increases hypothalamic norepinephrine levels to regulate thermoregulatory center function. iso-WAY-260022 is promising for research of vasomotor symptoms, such as menopausal hot flushes, night sweats.
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- No. CAS: 1214914-38-1
- Fòrmula: C21H31F3N2O2
- Peso molecular:400.48
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
Chemical Information
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No. CAS 1214914-38-1
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Peso molecular 400.48
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Fòrmula C21H31F3N2O2
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SMILES
C[C@H](N[C@@H](C1)C)CN1C[C@@H](C2=CC(OC(F)(F)F)=CC=C2)C3(CCCCC3)O
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Synonyms
iso-NRI-022
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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