L-162537
L-162537 is a competitive human angiotensin II receptor 1 (AT1) and receptor 2 (AT2) antagonist with an IC50=1.7 nM for AT1. L-162537 inhibits Ang II-mediated vasoconstriction, blood pressure elevation and related pathological signaling pathways. L-162537 is promising for research of angiotensin II-related cardiovascular diseases such as hypertension.
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- No. CAS: 167027-99-8
- Fòrmula: C38H32N8O2
- Peso molecular:632.71
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Ver todos los productos específicos de isoformas Angiotensin Receptor
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Actividad biológica
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AT1 Receptor 1.7 nM (IC50) |
AT2 Receptor |
Chemical Information
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No. CAS 167027-99-8
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Peso molecular 632.71
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Fòrmula C38H32N8O2
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SMILES
CCCC1=NC2=C(C(N1CC3=CC=C(C4=C(C5=NNN=N5)C=CC=C4)C=C3)=O)C=C(N(CC6=CN=CC=C6)C(C7=CC=CC=C7)=O)C=C2
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-162537 Related Classifications
HY-108120 Related Classifications
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