Lepidozin G
Lepidozin G inhibits the growth of a panel of cancer cell lines with IC50 values ranging from 4.2 ± 0.2 to 5.7 ± 0.5 μM. Lepidozin G induces PC-3 cell death via mitochondrial-related apoptosis.
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- No. CAS: 2869125-43-7
- Fòrmula: C30H48O4
- Peso molecular:472.70
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
4.4 μM
Compound: 7
|
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human A549 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 34797067] |
| NCI-H3255 | IC50 |
5.7 μM
Compound: 7
|
Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H3255 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 34797067] |
| NCI-H446 | IC50 |
5 μM
Compound: 7
|
Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human NCI-H446 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 34797067] |
| PC-3 | IC50 |
4.2 μM
Compound: 7
|
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
Cytotoxicity against human PC-3 cells assessed as inhibition of cell growth incubated for 48 hrs by MTT assay
|
[PMID: 34797067] |
Chemical Information
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No. CAS 2869125-43-7
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Peso molecular 472.70
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Fòrmula C30H48O4
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SMILES
CC(C(CC[C@@H](C)[C@@]1([H])[C@H](O)C[C@@]2(C)[C@]3([H])CC[C@]4([H])[C@@](CC[C@H](O)C4(C)C)(O)CC3=CC[C@@]21C)=O)=C
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)