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Referencia número: HY-181915

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PB2-IN-3

PB2-IN-3 (Compound 11) is a PB2 inhibitor. PB2-IN-3 exhibits antiviral activity against Influenza A H1N1 and H3N2 strains. PB2-IN-3 can be used in studies related to influenza A virus infection.

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Fòrmula: C₂₆H₂₉F₂N₇O₃
Peso molecular:525.55

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

PB2-IN-3 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- In Vitro
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
Bioz

Actividad biológica

Descripciòn

In Vitro

PB2-IN-3 exhibits antiviral activity against the Influenza A H3N2 strain in MDCK cells, with an IC₅₀ of 0.011 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Peso molecular 525.55
Fòrmula C₂₆H₂₉F₂N₇O₃
SMILES

O=C([C@@H]1CN(C(N[C@H]2C(CC3)CCC3[C@@H]2NC4=NC(C5=CNC6=NC=C(F)C=C65)=NC=C4F)=O)CCC1)O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Hu Q, et al. Design, Synthesis, Molecular Dynamics Simulations, and Biological Evaluation of PB2 Inhibitors as Anti-Influenza A Virus Agent. ACS Med Chem Lett. 2026 Mar 2;17(3):688-694. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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