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Referencia número: HY-149323

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SDH-IN-4

SDH-IN-4 (compound B6) is a selective inhibitor against succinate dehydrogenase (SDH) with an IC₅₀ value of 0.28 μg/mL. SDH-IN-4 has highly efficient and broad-spectrum antifungal activity, against R. solani with an EC₅₀ value of 0.23 μg/mL.

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No. CAS: 2982993-88-2
Fòrmula: C₁₁H₉Cl₂F₃N₄O₂S
Peso molecular:389.18

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

SDH-IN-4 Chemical Structure

No. CAS: 2982993-88-2

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Actividad biológica
- Descripciòn
- In Vitro
- In Vivo
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Bioz

Actividad biológica

Descripciòn

In Vitro

SDH-IN-4 (10 μg/mL, 3-5 days) inhibits mycelium growth of fungal R. solani, F. graminearum, B. cinerea and A. solani^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

SDH-IN-4 (100 μg/mL, 5 days) inhibits R. solani in detached rice leaves was 87.48%^[1].
SDH-IN-4 (20 μg/mL, 0.5-3 h) inhibits the growth and development of mycelia of R. solani and causes serious damage to the mycelial cell membrane^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 2982993-88-2
Peso molecular 389.18
Fòrmula C₁₁H₉Cl₂F₃N₄O₂S
SMILES

O=S(C1=C(C)NN=C1C(F)(F)F)(NNC2=CC=C(Cl)C=C2Cl)=O
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Chai JQ, et al. Potential Succinate Dehydrogenase Inhibitors Bearing a Novel Pyrazole-4-sulfonohydrazide Scaffold: Molecular Design, Antifungal Evaluation, and Action Mechanism. J Agric Food Chem. 2023 Jun 21;71(24):9266-9279. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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